Results 111 to 120 of about 12,934,423 (302)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
A Study of the Colombian Stock Market with Multivariate Functional Data Analysis (FDA)
MathematicsIn this work, Functional Data Analysis (FDA) is used to detect behavioral patterns in the Bolsa de Valores de Colombia (BVC) in reaction to the global crises caused by COVID-19 and the war in Ukraine.
Deivis Rodríguez Cuadro +3 more
doaj +1 more source
Functional data analysis for computational biology
Bioinformatics, 2019 Abstract Supplementary information: Supplementary data are available at Bioinformatics online.
Marzia A. Cremona +5 more
openaire +5 more sources
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Bayesian Functional Data Analysis Using WinBUGS
Journal of Statistical Software, 2010 We provide user friendly software for Bayesian analysis of functional data models using WinBUGS 1.4. The excellent properties of Bayesian analysis in this context are due to: (1) dimensionality reduction, which leads to low dimensional projection bases; (
Ciprian M. Crainiceanu +1 more
doaj
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Functional Data Analysis of Payment Systems
Nonlinear Analysis, 2002 In this paper for a credit cards payment system as robust predictor of transactions number and transactions intensity is proposed by means of functional autoregressive model.
A. Laukaitis, A. Račkauskas
doaj
Diagnosis of Mechanical Rotor Faults in Drones Using Functional Gaussian Mixture Classifier
AerospaceThe article presents the topic of propeller damage detection on unmanned multirotor drones. Propeller damage is dangerous as it can negatively affect the flight of a drone or lead to hazardous situations.
Bartosz Bartoszewski +2 more
doaj +1 more source