Results 131 to 140 of about 3,338,515 (259)

Beyond scalar metrics: functional data analysis of postprandial continuous glucose monitoring in the AEGIS study. [PDF]

BMC Med Res Methodol
Matabuena M, Sartini J, Gude F.
europepmc   +1 more source

Functional data analysis for longitudinal data with informative observation times. [PDF]

Biometrics, 2023
Weaver C, Xiao L, Lu W.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Functional data analysis of FSH and inhibin B levels in four ovulatory cycles shows a changing oscillatory interaction during the follicular phase. [PDF]

Front Endocrinol (Lausanne)
Usala SJ, Trindade AA, Vineyard DD.
europepmc   +1 more source

The dynamics of ideology drift among U.S. Supreme Court justices: A functional data analysis. [PDF]

PLoS One, 2022
Zhou X, Müller HG.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Contrasting pre-vaccine COVID-19 waves in Italy through functional data analysis. [PDF]

Sci Rep
Boschi T, Di Iorio J, Testa L, Cremona MA, Chiaromonte F.   +4 more
europepmc   +1 more source

Functional data analysis and visualisation of three-dimensional surface shape. [PDF]

J R Stat Soc Ser C Appl Stat, 2021
Katina S, Vittert L, W Bowman A.
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Genomic Anomaly Detection with Functional Data Analysis. [PDF]

Genes (Basel)
Kanjilal R, Campelo Dos Santos AL, Arnab SP, DeGiorgio M, Assis R.   +4 more
europepmc   +1 more source