Results 61 to 70 of about 6,800,650 (283)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Smoothing splines of apex predator movement: Functional modeling strategies for exploring animal behavior and social interactions

open access: yesEcology and Evolution, 2021
The collection of animal position data via GPS tracking devices has increased in quality and usage in recent years. Animal position and movement, although measured discretely, follows the same principles of kinematic motion, and as such, the process is ...
Andrew B. Whetten
doaj   +1 more source

Analysing musical performance through functional data analysis: rhythmic structure in Schumann's Träumerei [PDF]

open access: yes, 2009
Functional data analysis (FDA) is a relatively new branch of statistics devoted to describing and modelling data that are complete functions. Many relevant aspects of musical performance and perception can be understood and quantified as dynamic ...
Almansa, J   +1 more
core   +2 more sources

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Analysis Choices Impact Movement Evaluation: A Multi-Aspect Inferential Method Applied to Kinematic Curves of Vertical Hops in Knee-Injured and Asymptomatic Persons

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Three-dimensional human motion analysis provides in-depth understanding in order to optimize sports performance or rehabilitation following disease or injury.
Johan Strandberg   +3 more
doaj   +1 more source

Localization processes for functional data analysis

open access: yesAdvances in Data Analysis and Classification, 2022
We propose an alternative to $k$-nearest neighbors for functional data whereby the approximating neighboring curves are piecewise functions built from a functional sample. Using a locally defined distance function that satisfies stabilization criteria, we establish pointwise and global approximation results in function spaces when the number of data ...
Antonio Elías   +2 more
openaire   +3 more sources

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash   +4 more
wiley   +1 more source

Application of Functional Principal Component Analysis in the Spatiotemporal Land-Use Regression Modeling of PM2.5

open access: yesAtmosphere, 2023
Functional data are generally curves indexed over a time domain, and land-use regression (LUR) is a promising spatial technique for generating high-resolution spatial estimation of retrospective long-term air pollutants.
Mahmood Taghavi   +6 more
doaj   +1 more source

Search for Evergreens in Science: A Functional Data Analysis

open access: yes, 2017
Evergreens in science are papers that display a continual rise in annual citations without decline, at least within a sufficiently long time period. Aiming to better understand evergreens in particular and patterns of citation trajectory in general, this
Mei, Yajun, Wang, Jian, Zhang, Ruizhi
core   +1 more source

Weakly dependent functional data [PDF]

open access: yes, 2010
Functional data often arise from measurements on fine time grids and are obtained by separating an almost continuous time record into natural consecutive intervals, for example, days.
Hörmann, Siegfried, Kokoszka, Piotr
core   +1 more source

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