Results 51 to 60 of about 535,015 (301)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
How functional fitness relates to muscular power among older adults [PDF]
, 2014 The current study examined the relationship between functional fitness measures and muscular power among older adults. A 30-second chair stand test, 10-meter habitual walking test, and an 8-foot up-and-go test were all used as measures of functional ...
Moix, Jessica Mae
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Effect of modified Khon dance performance on functional fitness in older Thai persons [PDF]
Journal of Health Research, 2018 Purpose - Aging population is on the rise around the world. Strategies to improve quality of life in this population are being implemented. Exercise is one of those strategies that has been proven to be effective as it produces many health benefits.
Ladawan Chutimakul +3 more
doaj +1 more source
Evolutionary dynamics from a variational principle
, 2009 We demonstrate with a thought experiment that fitness-based population dynamical approaches to evolution are not able to make quantitative, falsifiable predictions about the long-term behavior of evolutionary systems. A key characteristic of evolutionary
Hanel, Rudolf +2 more
core +1 more source
Multi-objective improvement of software using co-evolution and smart seeding [PDF]
, 2008 Optimising non-functional properties of software is an important part of the implementation process. One such property is execution time, and compilers target a reduction in execution time using a variety of optimisation techniques. Compiler optimisation
Abbass, H +15 more
core +3 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Resting state functional connectivity in the default mode network and aerobic exercise in young adults [PDF]
, 2017 Around the world Alzheimer’s Disease (AD) is on the rise. Previous studies have shown the default mode network (DMN) sees changes with AD progression as the disease erodes away cortical areas.
Goss, Andrew
core
Bifurcation into functional niches in adaptation [PDF]
, 2004 One of the central questions in evolutionary biology concerns the dynamics of adaptation and diversification. This issue can be addressed experimentally if replicate populations adapting to identical environments Call be investigated in detail.
Adami, Christoph, White, Justin S.
core +2 more sources
Robust Non-Parametric Function Fitting
Journal of the Royal Statistical Society Series B: Statistical Methodology, 1984 SUMMARY A robust non-parametric function fitting method is introduced. The estimate is motivated from the theory of M-estimation and of kernel estimation of regression functions. Consistency and asymptotic normality are shown. Bias and variance rates are the same as those previously obtained by Gasser and Müller (1979) for linear ...
Härdle, W., Gasser, T.
openaire +2 more sources