Results 111 to 120 of about 903,985 (315)

Investigating consumer knowledge and behaviour in the context of functional foods [PDF]

The future of functional foods will depend on the extent to which they are accepted by consumers. Results are presented from a questionnaire that investigated consumers’ self-reported knowledge, behavioural intentions and purchasing behaviour regarding ...
Hall, Clare
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Research Progress of Crustacean Allergens and Allergens Specific Immunological Products

Shipin gongye ke-ji
Crustaceans are a prevalent source of food allergies in China. Despite efforts to avoid consuming allergenic foods, there is currently no known remedy that effectively treats these allergies.
Mengsi LI, Fei XIA, Qingmei LIU, Sujie HUANG, Yibin LU, Fei HUAN, Meng LIU, Yixiang LIU, Guangming LIU   +8 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

An Analysis of Financing Innovation and Commercialization in Canada's Functional Food and Nutraceutical Sector [PDF]

Growing consumer interest in functional foods and nutraceuticals has been seen as a significant business opportunity for the agri-food sector. Many of the new firms in this sector are small and medium sized enterprises (SMEs).
Herath, Deepananda P.B., Henson, Spencer J., Sparling, David, Cranfield, John A.L.   +3 more
core   +1 more source

Maternal gestational diabetes mellitus leads to adverse growth patterns and disease risk in offspring in vivo: evidence from cross-generational effects on gut microbiota

BMC Microbiology
Background Gestational diabetes mellitus (GDM) is an important risk factor for metabolic diseases such as obesity in its offspring, and this effect may be mediated by altering the infant’s gut microbiota.
Ting Yao, Yan Xiong, Qiang Hu, Yuhan Chen, Dan Li, Jiai Yan, Ju Yang, Yingyu Wang, Hong Cao, Feng Zhang, Ruijuan Zhuang, Jing Sun   +11 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Intratumoral delivery of probiotic Ligilactobacillus salivarius H22A013 modulates the melanoma microenvironment and enhances trametinib efficacy

BMC Microbiology
Melanoma, an aggressive and frequently metastatic skin cancer, demands more effective therapies. While probiotics modulate the gut–tumor axis, their indirect action and the use of engineered strains raise concerns over variability and safety.
Dongyu Zhen, Zhe Han, Zhihan Yang, Haiyang Tu, Xinlei Liu, Jiachao Zhang, Dongxue Huo   +6 more
doaj   +1 more source

A Novel Sesquiterpene from Callistephus chinensis Improves Alcohol-Induced Liver Disease by Regulating the AMPK/NF-κB Signaling Pathway and Gut Flora

Molecules
Alcoholic liver disease (ALD) caused by excessive alcohol consumption poses a serious threat to human health. Callistephus chinensis (L.) Nees is an herb of the Asteraceae family that has good results in the prevention and treatment of a variety of liver
Bingxin Zhang, Ning Wang, Xiaoxu Chen, Nan Yang, Ying Zhao, Xiaoshu Zhang   +5 more
doaj   +1 more source