The snoRNA-like lncRNA LNC-SNO49AB drives leukemia by activating the RNA-editing enzyme ADAR1
Cell Discovery, 2022 Long noncoding RNAs (lncRNAs) are usually 5′ capped and 3′ polyadenylated, similar to most typical mRNAs. However, recent studies revealed a type of snoRNA-related lncRNA with unique structures, leading to questions on how they are processed and how they
Wei Huang +11 more
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Functional analysis of the Arabidopsis TETRASPANIN gene family in plant growth and development [PDF]
, 2015 TETRASPANIN (TET) genes encode conserved integral membrane proteins that are known in animals to function in cellular communication during gamete fusion, immunity reaction and pathogen recognition.
Himanen, Kristiina +6 more
core +1 more source
Bacterial protein interaction networks: connectivity is ruled by gene conservation, essentiality and function [PDF]
, 2020 Protein-protein interaction (PPI) networks are the backbone of all processes in living cells. In this work we relate conservation, essentiality and functional repertoire of a gene to the connectivity $k$ of the corresponding protein in the PPI networks ...
Cimini, Giulio +2 more
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Genome-Wide Analysis of Glycine soja Response Regulator GsRR Genes Under Alkali and Salt Stresses
Frontiers in Plant Science, 2018 Soil salt-alkalization is a dramatic challenging factor for plant growth. Wild soybean (Glycine soja) exhibits a favorable trait of superior tolerance to salt-alkali stress, and recent discoveries show that response regulator family genes are involved in
Chao Chen +8 more
doaj +1 more source
Functional Profiling of Transcription Factor Genes in Neurospora crassa. [PDF]
, 2017 Regulation of gene expression by DNA-binding transcription factors is essential for proper control of growth and development in all organisms. In this study, we annotate and characterize growth and developmental phenotypes for transcription factor genes ...
Bekman, Thomas +17 more
core +1 more source
New insight into circRNAs: characterization, strategies, and biomedical applications
Experimental Hematology & Oncology, 2023 Circular RNAs (circRNAs) are a class of covalently closed, endogenous ncRNAs. Most circRNAs are derived from exonic or intronic sequences by precursor RNA back-splicing.
Xin-Yi Feng +5 more
doaj +1 more source
Two Amphioxus ApeC-Containing Proteins Bind to Microbes and Inhibit the TRAF6 Pathway
Frontiers in Immunology, 2021 The apextrin C-terminal (ApeC) domain is a class of newly discovered protein domains with an origin dating back to prokaryotes. ApeC-containing proteins (ACPs) have been found in various marine and aquatic invertebrates, but their functions and the ...
Jin Li +19 more
doaj +1 more source
Targeted sequencing identifies genetic polymorphisms of flavin-containing monooxygenase genes contributing to susceptibility of nicotine dependence in European American and African American [PDF]
, 2017 BACKGROUND: Smoking is a leading cause of preventable death. Early studies based on samples of twins have linked the lifetime smoking practices to genetic predisposition.
Beuten +49 more
core +2 more sources
htsint: a Python library for sequencing pipelines that combines data through gene set generation [PDF]
, 2015 Background: Sequencing technologies provide a wealth of details in terms of genes, expression, splice variants, polymorphisms, and other features. A standard for sequencing analysis pipelines is to put genomic or transcriptomic features into a context of
Bonneaud, Camille +2 more
core +3 more sources
Frontiers in Plant Science, 2018 Seed dormancy and germination are regulated by complex mechanisms controlled by diverse hormones and environmental cues. Abscisic acid (ABA) promotes seed dormancy and inhibits seed germination and post-germination growth.
Yu Ping Zhou +15 more
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