Results 21 to 30 of about 1,597,523 (269)

SNAPper: gene order predicts gene function [PDF]

open access: yesBioinformatics, 2002
Abstract Summary: SNAPper is a network service for predicting gene function based on the conservation of gene order. Availability: The SNAPper server is available at http://pedant.gsf.de/snapper. SNAPper-based functional predictions will soon be offered as part of the PEDANT genome analysis server http://pedant.gsf.de.
Grigory Kolesov   +2 more
openaire   +2 more sources

Systematic comparison of tools used for m6A mapping from nanopore direct RNA sequencing

open access: yesNature Communications, 2023
Direct RNA sequencing using nanopore platform can be used to detect N6-methyladenosine (m6A) modifications on mRNAs. Here the authors systematically compare tools used for m6A detection from nanopore direct sequencing.
Zhen-Dong Zhong   +11 more
doaj   +1 more source

Features of Functional Human Genes [PDF]

open access: yes, 2020
Abstract Proteins and non-coding RNAs are functional products of the genome that carry out the bulk of crucial cellular processes. With recent technological advances, researchers can sequence genomes in the thousands as well as probe for specific genomic activities of multiple species and conditions.
Helena B. Cooper, Paul P. Gardner
openaire   +1 more source

High-precision mapping reveals rare N 6 -deoxyadenosine methylation in the mammalian genome

open access: yesCell Discovery, 2022
N 6-deoxyadenosine methylation (6mA) is the most widespread type of DNA modification in prokaryotes and is also abundantly distributed in some unicellular eukaryotes. However, 6mA levels are remarkably low in mammals.
Li-Qian Chen   +12 more
doaj   +1 more source

A probabilistic view of gene function [PDF]

open access: yesNature Genetics, 2004
Cells are controlled by the complex and dynamic actions of thousands of genes. With the sequencing of many genomes, the key problem has shifted from identifying genes to knowing what the genes do; we need a framework for expressing that knowledge. Even the most rigorous attempts to construct ontological frameworks describing gene function (e.g., the ...
Andrew G, Fraser, Edward M, Marcotte
openaire   +2 more sources

Identification and Transcriptomic Analyses of Two Endophytic Fungi WDR2 and WDR5 from Wild Soybean Elucidates Mechanistic Aspects of Alkali Stress Tolerance

open access: yesJournal of Fungi
Soil alkalinization constitutes a significant abiotic stress factor that severely constrains global agricultural productivity. The application of alkali-tolerant endophytes represents a promising strategy for enhancing crop resilience. This study focused
Jiali Tian   +12 more
doaj   +1 more source

Transcriptome and Physio-Biochemical Profiling Reveals Differentially Expressed Genes in Seedlings from Aerial and Subterranean Seeds Subjected to Drought Stress in Amphicarpaea edgeworthii Benth

open access: yesAgronomy
Drought stress represents a prevalent environmental challenge that significantly impedes plant growth. The Chinese hog-peanut (Amphicarpaea edgeworthii Benth.), an amphicarpic legume, can produce both aerial seeds (ASs) and subterranean seeds (SSs ...
Jiancheng Kou   +9 more
doaj   +1 more source

Cell Cycle Regulation by Alternative Polyadenylation of CCND1

open access: yesScientific Reports, 2018
Global shortening of 3′UTRs by alternative polyadenylation (APA) has been observed in cancer cells. However, the role of APA in cancer remains unknown.
Qiong Wang   +6 more
doaj   +1 more source

DDX23, an Evolutionary Conserved dsRNA Sensor, Participates in Innate Antiviral Responses by Pairing With TRIF or MAVS

open access: yesFrontiers in Immunology, 2019
DExD/H-box helicases play essential roles in RNA metabolism, and emerging data suggests that they have additional functions in antiviral immunity across species.
Jie Ruan   +12 more
doaj   +1 more source

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