Results 41 to 50 of about 6,173,071 (306)

Hunting for Functionally Analogous Genes [PDF]

open access: yes, 2000
Evidence indicates that members of many gene families in the genome of an organism tend to have homologues both within their own genome and in the genomes of other organisms. Amongst these homologues, typically only one or a few per genome perform an analogous function in their genome.
Michael T. Hallett, Jens Lagergren
openaire   +2 more sources

SNAPper: gene order predicts gene function [PDF]

open access: yesBioinformatics, 2002
Abstract Summary: SNAPper is a network service for predicting gene function based on the conservation of gene order. Availability: The SNAPper server is available at http://pedant.gsf.de/snapper. SNAPper-based functional predictions will soon be offered as part of the PEDANT genome analysis server http://pedant.gsf.de.
Grigory Kolesov   +2 more
openaire   +2 more sources

High-throughput trapping of secretory pathway genes in mouse embryonic stem cells [PDF]

open access: yes, 2006
High-throughput gene trapping is a random approach for inducing insertional mutations across the mouse genome. This approach uses gene trap vectors that simultaneously inactivate and report the expression of the trapped gene at the insertion site, and ...
Hansen, J.   +17 more
core   +1 more source

Expression profiles of genes regulating dairy cow fertility: recent findings, ongoing activities and future possibilities [PDF]

open access: yes, 2008
Subfertility has negative effects for dairy farm profitability, animal welfare and sustainability of animal production. Increasing herd sizes and economic pressures restrict the amount of time that farmers can spend on counteractive management Genetic ...
Pas, M.F.W., te   +4 more
core   +1 more source

Systematic comparison of tools used for m6A mapping from nanopore direct RNA sequencing

open access: yesNature Communications, 2023
Direct RNA sequencing using nanopore platform can be used to detect N6-methyladenosine (m6A) modifications on mRNAs. Here the authors systematically compare tools used for m6A detection from nanopore direct sequencing.
Zhen-Dong Zhong   +11 more
doaj   +1 more source

Models incorporating chromatin modification data identify functionally important p53 binding sites [PDF]

open access: yes, 2013
Genome-wide prediction of transcription factor binding sites is notoriously difficult. We have developed and applied a logistic regression approach for prediction of binding sites for the p53 transcription factor that incorporates sequence information ...
Barker, Daniel   +2 more
core   +1 more source

Features of Functional Human Genes [PDF]

open access: yes, 2020
Abstract Proteins and non-coding RNAs are functional products of the genome that carry out the bulk of crucial cellular processes. With recent technological advances, researchers can sequence genomes in the thousands as well as probe for specific genomic activities of multiple species and conditions.
Helena B. Cooper, Paul P. Gardner
openaire   +1 more source

Facilitating functional annotation of chicken microarray data [PDF]

open access: yes, 2009
Background Modeling results from chicken microarray studies is challenging for researchers due to little functional annotation associated with these arrays.
Burgess Shane C   +14 more
core   +1 more source

A probabilistic view of gene function [PDF]

open access: yesNature Genetics, 2004
Cells are controlled by the complex and dynamic actions of thousands of genes. With the sequencing of many genomes, the key problem has shifted from identifying genes to knowing what the genes do; we need a framework for expressing that knowledge. Even the most rigorous attempts to construct ontological frameworks describing gene function (e.g., the ...
Andrew G, Fraser, Edward M, Marcotte
openaire   +2 more sources

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