Results 51 to 60 of about 6,173,071 (306)

Identification and Transcriptomic Analyses of Two Endophytic Fungi WDR2 and WDR5 from Wild Soybean Elucidates Mechanistic Aspects of Alkali Stress Tolerance

open access: yesJournal of Fungi
Soil alkalinization constitutes a significant abiotic stress factor that severely constrains global agricultural productivity. The application of alkali-tolerant endophytes represents a promising strategy for enhancing crop resilience. This study focused
Jiali Tian   +12 more
doaj   +1 more source

DDX23, an Evolutionary Conserved dsRNA Sensor, Participates in Innate Antiviral Responses by Pairing With TRIF or MAVS

open access: yesFrontiers in Immunology, 2019
DExD/H-box helicases play essential roles in RNA metabolism, and emerging data suggests that they have additional functions in antiviral immunity across species.
Jie Ruan   +12 more
doaj   +1 more source

High-precision mapping reveals rare N 6 -deoxyadenosine methylation in the mammalian genome

open access: yesCell Discovery, 2022
N 6-deoxyadenosine methylation (6mA) is the most widespread type of DNA modification in prokaryotes and is also abundantly distributed in some unicellular eukaryotes. However, 6mA levels are remarkably low in mammals.
Li-Qian Chen   +12 more
doaj   +1 more source

Genetic variation in genes interacting with BRCA1/2 and risk of breast cancer in Cypriot population. [PDF]

open access: yes, 2010
Inability to correctly repair DNA damage is known to play a role in the development of breast cancer. Single nucleotide polymorphisms (SNPs) of DNA repair genes have been identified, which modify the DNA repair capacity, which in turn may affect the risk
Daniel, M   +9 more
core   +6 more sources

Transcriptome and Physio-Biochemical Profiling Reveals Differentially Expressed Genes in Seedlings from Aerial and Subterranean Seeds Subjected to Drought Stress in Amphicarpaea edgeworthii Benth

open access: yesAgronomy
Drought stress represents a prevalent environmental challenge that significantly impedes plant growth. The Chinese hog-peanut (Amphicarpaea edgeworthii Benth.), an amphicarpic legume, can produce both aerial seeds (ASs) and subterranean seeds (SSs ...
Jiancheng Kou   +9 more
doaj   +1 more source

Cell Cycle Regulation by Alternative Polyadenylation of CCND1

open access: yesScientific Reports, 2018
Global shortening of 3′UTRs by alternative polyadenylation (APA) has been observed in cancer cells. However, the role of APA in cancer remains unknown.
Qiong Wang   +6 more
doaj   +1 more source

Exogenous maltose enhances Zebrafish immunity to levofloxacin‐resistant Vibrio alginolyticus

open access: yesMicrobial Biotechnology, 2020
Summary Understanding the interplay between bacterial fitness, antibiotic resistance, host immunity and host metabolism could guide treatment and improve immunity against antibiotic‐resistant pathogens.
Ming Jiang   +5 more
doaj   +1 more source

Gene functional neighbourhoods as predictors of gene function

open access: yes, 2015
Roles of many genes in a typical genome are still unknown or only partially explored. Experiments that determine the gene function are expensive and time-consuming, necessitating development of novel computational methods to predict gene functions by using machine learning and knowledge discovery techniques.
Mihelčić, Matej   +2 more
openaire   +1 more source

Identification of protein coding genes in genomes with statistical functions based on the circular code [PDF]

open access: yes, 2002
A new statistical approach using functions based on the circular code classifies correctly more than 93 % of bases in protein (coding) genes and non-coding genes of human sequences. Based on this statistical study, a research software called "Analysis of
Lacan, Jérôme   +5 more
core   +1 more source

Epitranscriptomic subtyping, visualization, and denoising by global motif visualization

open access: yesNature Communications, 2023
Advances in sequencing technologies have empowered epitranscriptomic profiling at the single-base resolution. Putative RNA modification sites identified from a single high-throughput experiment may contain one type of modification deposited by different ...
Jianheng Liu   +5 more
doaj   +1 more source

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