Results 31 to 40 of about 56,894 (219)

A probabilistic view of gene function [PDF]

open access: yesNature Genetics, 2004
Cells are controlled by the complex and dynamic actions of thousands of genes. With the sequencing of many genomes, the key problem has shifted from identifying genes to knowing what the genes do; we need a framework for expressing that knowledge. Even the most rigorous attempts to construct ontological frameworks describing gene function (e.g., the ...
Andrew G, Fraser, Edward M, Marcotte
openaire   +2 more sources

Systematic comparison of tools used for m6A mapping from nanopore direct RNA sequencing

open access: yesNature Communications, 2023
Direct RNA sequencing using nanopore platform can be used to detect N6-methyladenosine (m6A) modifications on mRNAs. Here the authors systematically compare tools used for m6A detection from nanopore direct sequencing.
Zhen-Dong Zhong   +11 more
doaj   +1 more source

High-precision mapping reveals rare N 6 -deoxyadenosine methylation in the mammalian genome

open access: yesCell Discovery, 2022
N 6-deoxyadenosine methylation (6mA) is the most widespread type of DNA modification in prokaryotes and is also abundantly distributed in some unicellular eukaryotes. However, 6mA levels are remarkably low in mammals.
Li-Qian Chen   +12 more
doaj   +1 more source

Identification and Transcriptomic Analyses of Two Endophytic Fungi WDR2 and WDR5 from Wild Soybean Elucidates Mechanistic Aspects of Alkali Stress Tolerance

open access: yesJournal of Fungi
Soil alkalinization constitutes a significant abiotic stress factor that severely constrains global agricultural productivity. The application of alkali-tolerant endophytes represents a promising strategy for enhancing crop resilience. This study focused
Jiali Tian   +12 more
doaj   +1 more source

Transcriptome and Physio-Biochemical Profiling Reveals Differentially Expressed Genes in Seedlings from Aerial and Subterranean Seeds Subjected to Drought Stress in Amphicarpaea edgeworthii Benth

open access: yesAgronomy
Drought stress represents a prevalent environmental challenge that significantly impedes plant growth. The Chinese hog-peanut (Amphicarpaea edgeworthii Benth.), an amphicarpic legume, can produce both aerial seeds (ASs) and subterranean seeds (SSs ...
Jiancheng Kou   +9 more
doaj   +1 more source

Cell Cycle Regulation by Alternative Polyadenylation of CCND1

open access: yesScientific Reports, 2018
Global shortening of 3′UTRs by alternative polyadenylation (APA) has been observed in cancer cells. However, the role of APA in cancer remains unknown.
Qiong Wang   +6 more
doaj   +1 more source

DDX23, an Evolutionary Conserved dsRNA Sensor, Participates in Innate Antiviral Responses by Pairing With TRIF or MAVS

open access: yesFrontiers in Immunology, 2019
DExD/H-box helicases play essential roles in RNA metabolism, and emerging data suggests that they have additional functions in antiviral immunity across species.
Jie Ruan   +12 more
doaj   +1 more source

Exogenous maltose enhances Zebrafish immunity to levofloxacin‐resistant Vibrio alginolyticus

open access: yesMicrobial Biotechnology, 2020
Summary Understanding the interplay between bacterial fitness, antibiotic resistance, host immunity and host metabolism could guide treatment and improve immunity against antibiotic‐resistant pathogens.
Ming Jiang   +5 more
doaj   +1 more source

The Evolution and Function of Genes.

open access: yesAmerican scientist, 1949
Uploaded by Plazi for TaxoDros. We do not have abstracts.
openaire   +3 more sources

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