Results 31 to 40 of about 1,597,523 (269)

Exogenous maltose enhances Zebrafish immunity to levofloxacin‐resistant Vibrio alginolyticus

open access: yesMicrobial Biotechnology, 2020
Summary Understanding the interplay between bacterial fitness, antibiotic resistance, host immunity and host metabolism could guide treatment and improve immunity against antibiotic‐resistant pathogens.
Ming Jiang   +5 more
doaj   +1 more source

The Evolution and Function of Genes.

open access: yesAmerican scientist, 1949
Uploaded by Plazi for TaxoDros. We do not have abstracts.
openaire   +3 more sources

Epitranscriptomic subtyping, visualization, and denoising by global motif visualization

open access: yesNature Communications, 2023
Advances in sequencing technologies have empowered epitranscriptomic profiling at the single-base resolution. Putative RNA modification sites identified from a single high-throughput experiment may contain one type of modification deposited by different ...
Jianheng Liu   +5 more
doaj   +1 more source

Gene functional neighbourhoods as predictors of gene function

open access: yes, 2015
Roles of many genes in a typical genome are still unknown or only partially explored. Experiments that determine the gene function are expensive and time-consuming, necessitating development of novel computational methods to predict gene functions by using machine learning and knowledge discovery techniques.
Mihelčić, Matej   +2 more
openaire   +1 more source

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille   +9 more
wiley   +1 more source

New Insights Into the Lineage-Specific Expansion and Functional Diversification of Lamprey AID/APOBEC Family

open access: yesFrontiers in Immunology, 2022
The AID/APOBEC family which converts cytidine to uridine on RNA or DNA experienced dynamic expansion in primates in order to resist exogenous viruses and endogenous retrotransposons.
Yan Chen   +9 more
doaj   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan   +1 more
wiley   +1 more source

Phytotoxic Effects of Bisphenol A on Growth and Physiology of Capsicum annuum L.

open access: yesHorticulturae
Bisphenol A (BPA) is a widely used chemical to produce raw materials in plastic production, which has led to its ubiquity in the natural environment and toxicity to both plants and humans.
Zilin Zhang   +7 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar   +7 more
wiley   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall   +2 more
wiley   +1 more source

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