The snoRNA-like lncRNA LNC-SNO49AB drives leukemia by activating the RNA-editing enzyme ADAR1
Cell Discovery, 2022 Long noncoding RNAs (lncRNAs) are usually 5′ capped and 3′ polyadenylated, similar to most typical mRNAs. However, recent studies revealed a type of snoRNA-related lncRNA with unique structures, leading to questions on how they are processed and how they
Wei Huang +11 more
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Systematic identification of functional plant modules through the integration of complementary data sources [PDF]
, 2012 A major challenge is to unravel how genes interact and are regulated to exert specific biological functions. The integration of genome-wide functional genomics data, followed by the construction of gene networks, provides a powerful approach to identify ...
Heyndrickx, Ken, Vandepoele, Klaas
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Lateral gene transfer between prokaryotes and multicellular eukaryotes: ongoing and significant? [PDF]
, 2009 The expansion of genome sequencing projects has produced accumulating evidence for lateral transfer of genes between prokaryotic and eukaryotic genomes. However, it remains controversial whether these genes are of functional importance in their recipient
Vera ID Ros +17 more
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Genome-Wide Analysis of Glycine soja Response Regulator GsRR Genes Under Alkali and Salt Stresses
Frontiers in Plant Science, 2018 Soil salt-alkalization is a dramatic challenging factor for plant growth. Wild soybean (Glycine soja) exhibits a favorable trait of superior tolerance to salt-alkali stress, and recent discoveries show that response regulator family genes are involved in
Chao Chen +8 more
doaj +1 more source
Functional analysis of the Arabidopsis TETRASPANIN gene family in plant growth and development [PDF]
, 2015 TETRASPANIN (TET) genes encode conserved integral membrane proteins that are known in animals to function in cellular communication during gamete fusion, immunity reaction and pathogen recognition.
Himanen, Kristiina +6 more
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Tissue-specific network-based genome wide study of amygdala imaging phenotypes to identify functional interaction modules [PDF]
, 2017 Motivation: Network-based genome-wide association studies (GWAS) aim to identify functional modules from biological networks that are enriched by top GWAS findings.
Alzheimer’s Disease Neuroimaging Initiative +10 more
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htsint: a Python library for sequencing pipelines that combines data through gene set generation [PDF]
, 2015 Background: Sequencing technologies provide a wealth of details in terms of genes, expression, splice variants, polymorphisms, and other features. A standard for sequencing analysis pipelines is to put genomic or transcriptomic features into a context of
Bonneaud, Camille +2 more
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New insight into circRNAs: characterization, strategies, and biomedical applications
Experimental Hematology & Oncology, 2023 Circular RNAs (circRNAs) are a class of covalently closed, endogenous ncRNAs. Most circRNAs are derived from exonic or intronic sequences by precursor RNA back-splicing.
Xin-Yi Feng +5 more
doaj +1 more source
Mangrove microniches determine the structural and functional diversity of enriched petroleum hydrocarbon-degrading consortia [PDF]
, 2010 In this study, the combination of culture enrichments and molecular tools was used to identify bacterial guilds, plasmids and functional genes potentially important in the process of petroleum hydrocarbon (PH) decontamination in mangrove microniches ...
Baek +81 more
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Frontiers in Plant Science, 2018 Seed dormancy and germination are regulated by complex mechanisms controlled by diverse hormones and environmental cues. Abscisic acid (ABA) promotes seed dormancy and inhibits seed germination and post-germination growth.
Yu Ping Zhou +15 more
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