Results 241 to 250 of about 2,594,564 (358)

Correction: c-Myc-driven glycolysis polarizes functional regulatory B cells that trigger pathogenic inflammatory responses

Signal Transduction and Targeted Therapy
Xu-Yan Wang, Yuan Wei, Bo Hu, Yuan Liao, Xiaodong Wang, Wen-Hua Wan, Chun-Xiang Huang, Mahepali Mahabati, Zheng-Yu Liu, Jing-Rui Qu, Xiao-Dan Chen, Dong-Ping Chen, Dong-Ming Kuang, Xue-Hao Wang, Yun Chen   +14 more
doaj   +1 more source

DeleteomeTools: utilizing a compendium of yeast deletion strain transcriptomes to identify co-functional genes. [PDF]

NAR Genom Bioinform
Neal ML, Choudhry SK, Aitchison JD.
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Habitat Heterogeneity of Nitrogen and Phosphorus Cycling Functional Genes in Rhizosphere Microorganisms of <i>Pinus tabuliformis</i> in Qinling Mountains, China. [PDF]

Microorganisms
Yang H, Pang Y, Yang Y, Wang D, Wang Y.
europepmc   +1 more source

MOESM6 of Genome-wide identification, characterisation and functional evaluation of WRKY genes in the sweet potato wild ancestor Ipomoea trifida (H.B.K.) G. Don. under abiotic stresses

, 2019
Yuxia Li, Lei Zhang, Panpan Zhu, Qinghe Cao, Jian Sun, Zongyun Li, Tao Xu   +6 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

CRISPR/Cas9-mediated genomic insertion of functional genes into Lactiplantibacillus plantarum WCFS1. [PDF]

Microbiol Spectr
Wiull K, Haugen LK, Eijsink VGH, Mathiesen G.   +3 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Screening of functional genes affecting the quality of translucent eggshell membranes based on RNA-seq analysis and DIA proteomics. [PDF]

Front Vet Sci
Han CH, Zhao XY, Wang CW, Xu LJ, Liu HG, Chen H, Zhou RY, Wang DH.   +7 more
europepmc   +1 more source

Retraction: Genome-Wide Analysis of the Dof Transcription Factor Gene Family Reveals Soybean-Specific Duplicable and Functional Characteristics

, 2016
Yong Guo, Lijuan Qiu, PLOS ONE Editors
openalex   +2 more sources