Results 51 to 60 of about 68,679 (255)
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye +33 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Children with functional motor limitations: The effects on family strengths
Sixty children with functional motor limitations (age range from 15 months to 7 years 3 months) and their parents participated in the study The objective was to explore the relationship of the severity of their restrictions on family strengths ...
Pirila, S +6 more
core +1 more source
Assistive technology access in longitudinal datasets: a global review
Functional limitations become more prevalent as populations age, emphasising an increasingly urgent need for assistive technology (AT). Critical to meeting this need trajectory is understanding AT access in older ages.
Jamie Danemayer +3 more
doaj +1 more source
Limits and singularities of normal functions [PDF]
We construct a collection of higher Chow cycles on certain surfaces which degenerate to an arrangement of planes in general position. When its degree is 4, this construction gives a new explicit proof of the Hodge-D-Conjecture for a certain type of K3 surfaces. As an application, we also construct a certain type of threefolds with non trivial Griffiths
openaire +4 more sources
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Assessment Tools for Identifying Functional Limitations Associated With Functional Ankle Instability
Assessment tools should identify functional limitations associated with functional ankle instability (FAI) by discriminating unstable from stable ...
Ross, Scott E. +3 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Functional task limitations in obese adults
Obesity is characterized by increased dimensions and mass. Functional task limitations and changes in the mechanical strategies used to complete functional tasks may be related independently to increased mass or increased dimensions.
Gilleard, Wendy L
core +1 more source

