Attomolar Detection of HIV‐1 With Label‐Free RCA‐rCRISPR on Smartphone
A new diagnostic strategy integrating rolling circle amplification (RCA) with a plasmid reporter–based ratiometric CRISPR (rCRISPR) system was developed to detect unfragmented HIV genomes with single‐digit attomolar sensitivity. The method quantifies targets using the plasmid relaxation ratio and employs a smartphone‐based mini‐gel device to enable ...
Noor Mohammad +12 more
wiley +1 more source
Conduction system pacing vs. biventricular pacing for cardiac resynchronization therapy in heart failure: a systematic review and meta-analysis considering randomized controlled trials and observational studies. [PDF]
Chauhan K +6 more
europepmc +1 more source
When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley +1 more source
Dietary Patterns and Nutritional Interventions for Cognitive Impairment in Parkinson's Disease: A Critical Narrative Review. [PDF]
Aldakheel A, Qadi N.
europepmc +1 more source
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas +6 more
wiley +1 more source
Prevalence and Outcomes of Suspected Dysphagia in Elderly Inpatients Undergoing Cardiac Rehabilitation: A Single-Center Observational Study. [PDF]
Miyawaki N, Takashima A.
europepmc +1 more source
This review comprehensively summarizes the atomic defects in TMDs for their applications in sustainable energy storage devices, along with the latest progress in ML methodologies for high‐throughput TEM data analysis, offering insights on how ML‐empowered microscopy facilitates bridging structure–property correlation and inspires knowledge for precise ...
Zheng Luo +6 more
wiley +1 more source
The Nova Protocol: a comprehensive multimodal longitudinal study among civilian survivors of a mass trauma event. [PDF]
Admon R +18 more
europepmc +1 more source
Language Impairment in Alzheimer's Disease: An Updated Narrative Review of Digital Assessment, Social Interventions, and Medical Treatment, 2016-2026. [PDF]
Klimova B.
europepmc +1 more source
Association of Lower-Limb Asymmetry with Falls, Physical Performance and Frailty in Older Adults: A Systematic Review. [PDF]
Kasicki K, Szymeczko K.
europepmc +1 more source

