Exploring the Effectiveness of Technology-Based Interventions in Aphasia Rehabilitation: A Systematic Review. [PDF]
Int J Lang Commun DisordAlhejji B +3 more
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Drone-delivered automated external defibrillators in prehospital emergency care: implementation evidence, bottlenecks, and conceptual integration with artificial intelligence and next-generation communications. [PDF]
Front Public HealthLi H +9 more
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In-Hospital Rehabilitation for Frailty Management May Improve Quality of Life in Patients Receiving Maintenance Dialysis: A Retrospective Observational Study. [PDF]
CureusYonemochi T +9 more
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Approaches for assessing the validity of a functional observational battery
Neurotoxicology and Teratology, 1990As neurobehavioral assessments during the preliminary stages of chemical testing are more widely undertaken, it is critical that the screening procedures utilized be valid indicators of neurobehavioral function and that they be sensitive, specific, and reliable.
V C Moser, Virginia C Moser
exaly +3 more sources
A Functional Observational Battery for Use in Canine Toxicity Studies: Development and Validation
International Journal of Toxicology, 2003The most commonly used nonrodent species in regulatory toxicity and safety assessment studies has been and remains the dog, with the beagle being the standard breed employed. Although a standard functional observational battery (FOB) or neurobehavioral screen for use in rodents (primarily rats) has been incorporated into rodent studies since the late ...
S C Gad
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The objective of this study was to establish a functional observational battery that provided a basic neurological and behavioral assessment fully compliant with requisite governmental regulatory guidelines.Accredited Laboratory Animal Technicians (ALAT) were trained to conduct neurobehavioral assessments in rhesus monkeys prior to and following ...
David Gauvin, Theodore J Baird
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Evaluation of Neurotoxicity Potential in Rats: The Functional Observational Battery
Current Protocols in Pharmacology, 2010AbstractThis unit describes the functional observational battery (FOB), a behavioral screening procedure commonly used in safety pharmacology and toxicology studies to assess potentially adverse effects of test agents on the central nervous system. The battery includes general observations and the determination of reactivity to various stimuli.
Aurélie, Boucard +4 more
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Several recent reports have demonstrated that acute solvent exposure in animals produces a profile of neurobehavioral effects similar to that of classical CNS depressant drugs such as the barbiturates and ethanol. The present investigation further delineated the behavioral pharmacology of three solvents [1,1,1-trichloroethane (TCE), ether, and ...
Jenny Wiley, Scott E Bowen, R L Balster
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The International Conference on Harmonisation's (ICH) Tripartite Guideline on Safety Pharmacology Studies for Human Pharmaceuticals has adopted the requirement that each new test substance must be tested for effects on the central nervous system prior to "first dose in man".
David Gauvin +2 more
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