Results 161 to 170 of about 549 (211)
Some of the next articles are maybe not open access.
Nucleosides, Nucleotides and Nucleic Acids, 1998
Abstract In this work a number of new designed mono- and bifunctional derivatives of oligonucleotides (deoxyribo-, ribo-series, and their 2′-O-methyl-, P-ethyl, methylphosphonate, and thiophosphate analogs) is described including those bearing reactive, stabilizing, and hydrophobic groups.
Elena P Ivanova
exaly +2 more sources
Abstract In this work a number of new designed mono- and bifunctional derivatives of oligonucleotides (deoxyribo-, ribo-series, and their 2′-O-methyl-, P-ethyl, methylphosphonate, and thiophosphate analogs) is described including those bearing reactive, stabilizing, and hydrophobic groups.
Elena P Ivanova
exaly +2 more sources
Electropolymerizable Thiophene–Oligonucleotides for Electrode Functionalization
ACS Applied Materials & Interfaces, 2022Inserting complex biomolecules such as oligonucleotides during the synthesis of polymers remains an important challenge in the development of functionalized materials. In order to engineer such a biofunctionalized interface, a single-step method for the covalent immobilization of oligonucleotides (ONs) based on novel electropolymerizable lipid ...
Getnet S. Kassahun +9 more
openaire +3 more sources
DIVERSITY OF OLIGONUCLEOTIDE FUNCTIONS
Annual Review of Biochemistry, 1995SELEX is a technology for the identification of high affinity oligonucleotide ligands. Large libraries of random sequence single-stranded oligonucleotides, whether RNA or DNA, can be thought of conformationally not as short strings but rather as sequence dependent folded structures with high degrees of molecular rigidity in solution.
L, Gold +3 more
openaire +3 more sources
Incorporation of an Aldehyde Function in Oligonucleotides
Bioconjugate Chemistry, 2001A nucleotide-like phosphoramidite building block that has the nucleic base replaced by the tert-butyldimethylsilyl-protected styrene glycol was synthesized. After the automatic synthesis of an oligonucleotide incorporating this synthon, the benzaldehyde function was generated by fluoride deprotection and oxidation by sodium periodate.
J M, Tilquin, M, Dechamps, E, Sonveaux
openaire +2 more sources
Biotechnology applications of proteins functionalized with DNA oligonucleotides
Trends in Biotechnology, 2023The functionalization of proteins with DNA through the formation of covalent bonds enables a wide range of biotechnology advancements. For example, single-molecule analytical methods rely on bioconjugated DNA as elastic biolinkers for protein immobilization.
Ipek Simay Gokulu, Scott Banta
openaire +2 more sources
Oligonucleotide probes functionalization of nanogap electrodes
ELECTROPHORESIS, 2017AbstractNanogap electrodes have attracted a lot of consideration as promising platform for molecular electronic and biomolecules detection. This is mainly for their higher aspect ratio, and because their electrical properties are easily accessed by current‐voltage measurements. Nevertheless, application of standard current‐voltages measurements used to
Rosa Letizia Zaffino +2 more
openaire +2 more sources
DNA Conjugates as Novel Functional Oligonucleotides
ChemInform, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
Takanori, Kubo +7 more
openaire +2 more sources
Aldehyde Functions in Synthetic Oligonucleotides
Nucleosides, Nucleotides and Nucleic Acids, 1995new nucleoside analogs with a masked aldehyde function have been synthesized and incorporated in oligodexoyribonucleotides. After unmasking the aldehyde function, the oligomers were easily coupled to biotin derivatives by reductive amination. Reversed phase HPLC proved to be an unvaluable tool to characterize and purify these conjugates.
M. Dechamps, E. Sonveaux
openaire +1 more source
Post‐Synthetic Functionalization of Triple Helix‐Forming Oligonucleotides
ChemInform, 2004AbstractFor Abstract see ChemInform Abstract in Full Text.
Alexandre S, Boutorine, Jian-Sheng, Sun
openaire +2 more sources
Methods to Characterize the Oligonucleotide Functionalization of Quantum Dots
Small, 2016Currently, DNA nanotechnology offers the most programmable, scalable, and accurate route for the self‐assembly of matter with nanometer precision into 1, 2, or 3D structures. One example is DNA origami that is well suited to serve as a molecularly defined “breadboard”, and thus, to organize various nanomaterials such as nanoparticles into hybrid ...
Richard, Weichelt +6 more
openaire +2 more sources