Results 41 to 50 of about 791,940 (315)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Stability of a generalized n-variable mixed-type functional equation in fuzzy modular spaces

Journal of Inequalities and Applications, 2021
This research paper deals with general solution and the Hyers–Ulam stability of a new generalized n-variable mixed type of additive and quadratic functional equations in fuzzy modular spaces by using the fixed point method.
Murali Ramdoss, Divyakumari Pachaiyappan, Choonkil Park, Jung Rye Lee   +3 more
doaj   +1 more source

Population-associated differences between the phase variable LPS biosynthetic genes of Helicobacter pylori

, 2006
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
Salaün, L, Saunders Nigel J, Salaün Laurence, Saunders, Nigel, Saunders, NJ, Laurence Salaün, Nigel J Saunders, Saunders, Nigel J., Saunders, Nigel J, Salaün, Laurence   +9 more
core   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Sparse Semi-Functional Partial Linear Single-Index Regression

Proceedings, 2018
The variable selection problem is studied in the sparse semi-functional partial linear model, with single-index type influence of the functional covariate in the response. The penalized least squares procedure is employed for this task.
Silvia Novo, Germán Aneiros, Philippe Vieu   +2 more
doaj   +1 more source

Estimates of solutions for parabolic differential and difference functional equations and applications [PDF]

Opuscula Mathematica, 2012
The theorems on the estimates of solutions for nonlinear second-order partial differential functional equations of parabolic type with Dirichlet's condition and for suitable implicit finite difference functional schemes are proved.
Lucjan Sapa
doaj   +1 more source

Variable metric methods for minimizing a class of nondifferentiable functions [PDF]

Mathematical Programming, 1981
We develop a class of methods for minimizing a nondifferentiable function which is the maximum of a finite number of smooth functions. The methods proceed by solving iteratively qquadratic programming problems to generate search directions. For efficiency the matrices in the quadratic programming problems are suggested to be updated in a variable ...
openaire   +2 more sources

Discrete Razumikhin-type technique and stability of the Euler-Maruyama method to stochastic functional differential equations

, 2013
A discrete stochastic Razumikhin-type theorem is established to investigate whether the Euler--Maruyama (EM) scheme can reproduce the moment exponential stability of exact solutions of stochastic functional differential equations (SFDEs).
Wu, Fuke, Kloeden, Peter E., Mao, Xuerong   +2 more
core   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source