Results 111 to 120 of about 6,527,060 (344)
Journal of Functional FoodsDoxorubicin (DOX) is a widely used chemotherapeutic agent, but its clinical application is limited by cardiotoxicity associated with oxidative stress, inflammation, and apoptosis. Cirsium setidens (C.
Ji-Hye Song +4 more
doaj +1 more source
Nanophotonic modal dichroism: mode-multiplexed modulators
, 2016 As the diffraction limit is approached, device miniaturization to integrate more functionality per area becomes more and more challenging. Here we propose a novel strategy to increase the functionality-per-area by exploiting the modal properties of a ...
Das, Susobhan +5 more
core +1 more source
Nanomedicine : nanotechnology, biology, and medicine, 2017 Extracellular vesicles (EVs) are nano-sized, lipid bilayer-enclosed particles involved in intercellular communication. EVs are increasingly being considered as drug delivery vehicles or as cell-free approach to regenerative medicine.
E. Mol +4 more
semanticscholar +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
HEUN FUNCTIONS VERSUS ELLIPTIC FUNCTIONS [PDF]
Difference Equations, Special Functions and Orthogonal Polynomials, 2007 Communication at the International Conference on Difference Equations, Special Functions and Applications, Munich, 25-30 july 2005, latex 2e, 20 ...
openaire +2 more sources
, 2017 Effective functionality of the gastrointestinal tract (GIT) and its health, are important factors in determining animal performance. Several, complex mechanisms are involved in the regulation of GIT functionality and health, therefore it is crucial to ...
P. Celi +5 more
semanticscholar +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Modulation of Target Antigen Density Improves CAR T-cell Functionality and Persistence
Clinical Cancer Research, 2019 Purpose: Chimeric antigen receptor T-cell (CART) therapy targeting CD22 induces remission in 70% of patients with relapsed/refractory acute lymphoblastic leukemia (ALL).
S. Ramakrishna +15 more
semanticscholar +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Frontiers in NutritionMetabolic dysfunction-associated steatotic liver disease (MASLD) is a global health issue that causes severe liver abnormalities and metabolic dysregulation, incurring substantial costs to healthcare systems.
Miri Park +8 more
doaj +1 more source