Results 111 to 120 of about 199,210 (278)

Benchmarking the fundamental parameters of Ap stars with optical long-baseline interferometric measurements (Corrigendum) [PDF]

, 2023
K. Perraut, M. S. Cunha, A. M. Romanovskaya, D. Shulyak, T. Ryabchikova, V. Hocdé, N. Nardetto, D. Mourard, A. Meilland, F. Morand, I. Tallon–Bosc, C. Farrington, Cyprien Lanthermann   +12 more
openalex   +1 more source

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source

Physical Parameters of 12,201 ASAS-SN Contact Binaries Determined by a Neural Network

The Astrophysical Journal Supplement Series
In the era of astronomical big data, more than one million contact binaries have been discovered. Traditional approaches of light-curve analysis are inadequate for investigating such an extensive number of systems.
Kai Li, Li-Heng Wang
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Tests of Disk-locking in T Tauri Stars of the Orion Nebula Cluster

The Astrophysical Journal
We look for specific correlations predicted by magnetospheric accretion models for young stars that assume disk-locking using stellar and accretion parameters derived from low-resolution HST-STIS spectra of 33 T Tauri stars in the Orion Nebula Cluster ...
Margaret A. Mueller, Christopher M. Johns-Krull, Keivan G. Stassun, Don M. Dixon   +3 more
doaj   +1 more source

Fundamental parameters of the Ap-stars GO And, 84 UMa, and $\kappa$ Psc. [PDF]

, 2021
A. M. Romanovskaya, D. Shulyak, T. Ryabchikova, T. Sitnova   +3 more
openalex  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Discoveries and Properties of EL CVn–type Binaries in the TESS Survey

The Astrophysical Journal
EL CVn–type systems represent a rare evolutionary stage in binary star evolution, providing ideal laboratories for investigating stable mass-transfer processes and the formation of extremely low-mass white dwarfs (ELM WDs).
Jianping Xiong, Zhenwei Li, Jiao Li, Xiaobin Zhang, Xiaodian Chen, Kaifan Ji, Zhanwen Han, Xuefei Chen   +7 more
doaj   +1 more source

The life cycles of Be viscous decretion discs: fundamental disc parameters of 54 SMC Be stars [PDF]

, 2018
L. R. Rímulo, Aulus Cavalieri Carciofí, R. G. Vieira, Th. Rivinius, D. M. Faes, André Luiz Figueiredo, K. S. Bjorkman, C. Georgy, M. R. Ghoreyshi, I. Soszyński   +9 more
openalex   +1 more source