Results 141 to 150 of about 201,996 (278)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Toward Early-type Eclipsing Binaries as Extragalactic Milestones. IV. Physical Properties of Three Detached O/B-type Systems in the LMC

open access: yesThe Astrophysical Journal
We present a complete set of physical parameters for three early-type eclipsing binary systems in the Large Magellanic Cloud (LMC): OGLE LMC-ECL-17660, OGLE LMC-ECL-18794, and HV 2274, together with the orbital solutions.
Mónica Taormina   +12 more
doaj   +1 more source

Determination of fundamental parameters and circumstellar properties for a sample of B[e] stars [PDF]

open access: bronze, 2010
M. F. Muratore   +4 more
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Mass Transfer and Loss in an Extremely Low-mass-ratio Semidetached Binary with a Pulsating A-type Star

open access: yesThe Astrophysical Journal
AY Gem is a short-period Algol-type eclipsing binary with a period of 3.05 days that is neglected for spectroscopic and photometric investigations. The first radial-velocity curves have been obtained for AY Gem by using LAMOST medium- and low-resolution ...
Hui-Ting Zhang   +2 more
doaj   +1 more source

Metallicity vs. Be phenomenon relation in the solar neighborhood

open access: yes, 2006
Fast rotation seems to be the mayor factor to trigger the Be phenomenon. Surface fast rotation can be favored by initial formation conditions, such as abundance of metals. We have observed 118 Be stars up to the apparent magnitudes V=9 mag.
Frémat, Y.   +3 more
core   +1 more source

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