Results 141 to 150 of about 199,210 (278)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

High-resolution Spectroscopic Analysis of Four Unevolved Barium Stars

open access: yesThe Astronomical Journal
A classical local thermodynamic equilibrium analysis, based on high-resolution spectroscopic data, is performed for a sample of three potential barium dwarf candidates and one star already recognized as such.
M. P. Roriz   +6 more
doaj   +1 more source

Fast Rotation vs. Metallicity

open access: yes, 2005
Fast rotation seems to be the major factor to trigger the Be phenomenon. Surface fast rotation can be favored by initial formation conditions such as metal abundance.
Fremat, Yves   +3 more
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Toward Early-type Eclipsing Binaries as Extragalactic Milestones. IV. Physical Properties of Three Detached O/B-type Systems in the LMC

open access: yesThe Astrophysical Journal
We present a complete set of physical parameters for three early-type eclipsing binary systems in the Large Magellanic Cloud (LMC): OGLE LMC-ECL-17660, OGLE LMC-ECL-18794, and HV 2274, together with the orbital solutions.
Mónica Taormina   +12 more
doaj   +1 more source

Determination of fundamental parameters and circumstellar properties for a sample of B[e] stars [PDF]

open access: bronze, 2010
M. F. Muratore   +4 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

A Study of Nine Extremely Low Mass Ratio-contact Binary Systems

open access: yesThe Astronomical Journal
Low-mass ratio systems (LMR) are a very interesting class of contact eclipsing binaries challenging the theoretical models of stability. These systems are also considered possible progenitors of the rare low-mass optical transients called red novae.
Eleni Lalounta   +4 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

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