2-(Furan-2-yl)-5-(2-nitrobenzyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one
The title compound, C20H16N2O4S, was prepared by introduction of a 2-nitrobenzyl group to 2-(furan-2-yl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one via an alkaline-catalysed reaction. The thiazepine ring adopts a twist-boat conformation.
De-Yong Ye, Yong Chu, Zhao-Hui Huang
doaj +2 more sources
Synthesis and Cytotoxic Activity of Some 3-Benzyl-5-Arylidenefuran-2(5H)-ones
3-Benzyl-furan-2(5H)-one (2a) and 3-(4-bromobenzyl)-furan-2(5H)-one (2b) were treated with TBDMSOTf and converted into the corresponding tert-butyldimethyl-silylfuran ethers.
Manoel Odorico Moraes +7 more
doaj +2 more sources
Direct 2(5H)-furanone annulation produces promising cross-coupling partners incorporating m- or p-bromo- and p-tosyloxyphenyl groups into the 5-position of a notable 2(5H)-furanone pharmacore.
Yuki Ban +3 more
doaj +2 more sources
The title compound, C20H33ClN2O3, was obtained via a tandem asymmetric Michael addition–elimination reaction of 3,4-dichloro-5-(S)-(l-menthyloxy)furan-2(5H)-one and 1-ethylpiperazine in the presence of potassium fluoride.
Jian-Hua Fu +3 more
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Araufuranone: A New Phytotoxic Tetrasubstituted Dihydrofuro[3,2-b]furan-2(5H)-One Isolated from Ascochyta araujiae. [PDF]
Araujia hortorum is a perennial vining plant species native to South America. It was introduced into many countries for ornamental and medicinal purposes as well as for its edible fruits, but it has become highly invasive, generating severe environmental
Masi M +5 more
europepmc +2 more sources
A combinatorial approach to the chemical synthesis and biological evaluation of 3,4,5-trisubstiituted furan-2(5H)-ones [PDF]
Many important natural products contain the furan-2(5H)-one structure. The structure of this molecule lends itself to manipulation using combinatorial techniques due to the presence of more than one site for the attachment of different suhstituents.
Langley, Christopher A.
core +8 more sources
Metal-Free, Mild, and Sustainable Synthesis of Bio-Based Polyesters via EDC/DMAP-Mediated Polycondensation: Structure-Property Relationships and Thermal Stability. [PDF]
We developed a mild, metal‐free EDC/DMAP‐mediated polycondensation platform for bio‐based polyesters from FDCA (2,5‐furandicarboxylic acid) and succinic acid, enabling access to homopolyesters from unsaturated and aliphatic diols as well as heteropolyesters prepared by one‐pot or sequential routes.
Pedraza L +5 more
europepmc +2 more sources
Scientific Opinion on Flavouring Group Evaluation 217, Revision 1 (FGE.217Rev1). Consideration of genotoxic potential for ?,?-unsaturated ketones and precursors from chemical subgroup 4.1 of FGE.19: Lactones [PDF]
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of 12 flavouring substances from subgroup 4.1 of FGE.19 in the Flavouring Group ...
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj +1 more source
Scientific opinion on Prosmoke BW 01
The EFSA Panel on Food Additives and Flavourings (FAF) was requested to evaluate the safety of Prosmoke BW 01 as a new smoke flavouring primary product, in accordance with Regulation (EC) No 2065/2003. Prosmoke BW01 is produced by pyrolysis of beechwood (
EFSA Panel on Food Additives and Flavourings (FAF) +29 more
doaj +1 more source
Nano-colloidal silica-tethered polyhedral oligomeric silsesquioxanes with eight branches of 3-aminopropyltriethoxysilane as high performance catalyst for the preparation of furan-2(5H)-ones [PDF]
An efficient and rapid method for the synthesis of 3,4,5-substituted furan-2 (5H)-ones has been achieved through a three-component reaction of aniline, dialkyl acetylenedicarboxylate, and aromatic aldehydes using nano-colloidal silica-tethered polyhedral
Hossein Shahbazi-Alavi +1 more
doaj +1 more source

