Results 21 to 30 of about 37,838,535 (141)

2-Amino-1-methyl-1H-imidazol-4(5H)-one dimethyl sulfoxide monosolvate [PDF]

, 2010
In the title compound, C4H7N3O·C2H6OS, creatinine [2-amino-1-methyl-1H-imidazol-4(5H)one] exists in the amine form. The ring is planar (r.m.s. deviation for all non-H atoms = 0.017 Å).
Bolte, Michael, Maya Tutughamiarso, Michael Bolte, Tutughamiarso, Maya Oktavia   +3 more
core   +1 more source

A Novel Approach to 5,5’-Diisopropyl-3,3’-bi-2H-cyclohepta[b]furan-2-one [PDF]

, 2007
5-Isopropyl-2H-cyclohepta[b]furan-2-one (1) reacted with DMSD to give dimethyl(5-isopropyl-2-oxo-2H-cyclohepta[b]furan-3-yl)sulfonium trifluoromethanesulfonate (2), which was treated with E(t)3N to give 5-isopropyl-3-methylthio-2H-cyclohepta[b]furan-2 ...
Yasunami, M, Ito, S, Kikuchi, S, Watanabe, M, Okada, K, Toyota, K, Higashi, J, Shoji, T, Morita, N   +8 more
core   +1 more source

Polyketides from the Halotolerant Fungus Myrothecium sp. GS-17

Molecules, 2013
Two new polyketides, myrothecol (1) and 5-hydroxy-3-methyl-4-(1- hydroxylethyl)-furan-2(5H)-one (2), were isolated from the fermentation broth of the halotolerant fungus Myrothecium sp.
Tao Liu, Jing Zhu, Song-Ya Zhang, Zhan-Lin Li, Li-Ping Guan, Hua-Qi Pan, Xin Wu, Jiao Bai, Hui-Ming Hua   +8 more
doaj   +1 more source

Reaction of 2H-Cyclohepta[b]furan-2-ones with Pyridinium Salts of Trifluoromethanesulfonic Anhydride [PDF]

, 2006
2H-Cyclohepta[b]furan-2-one (1) reacted with TPT, electrophilically to give 3-dihydropyridinyl-2H-cyclohepta[b]furan-2-one and subsequent treatment with sodium hydroxide in ethanol gave 3-(4-pyridinyl)-2H-cyclohepta[b]furan-2-one in excellent yields ...
Ito, S, Kikuchi, S, Nakashima, M, Toyota, K, Matsuki, T, Shoji, T, Morita, N   +6 more
core   +1 more source

Effect of a Cytoprotective Dose of Dehydroleucodine, Xanthatin, and 3-Benzyloxymethyl-5H-furan-2-one on Gastric Mucosal Lesions Induced by Mast Cell Activation [PDF]

, 2021
The aim of this study was to determine whether the lactones dehydroleucodine, xanthatin and 3-benzyloxymethyl-5H-furan-2-one, would be effective in an animal model of gastric ulcer induced by mast cell activation.
María Laura Mariani, Vera, Mariano Ezequiel, Penissi, Alicia Beatriz, Mariano Ezequiel Vera, Mariani, María Laura Lucía, Alicia Beatriz Penissi, Cristina Aguilera, Aguilera, Cristina   +7 more
core   +1 more source

A Modular Synthesis of C5‐Sulfenyl Thiazoles via an Intermolecular Pummerer Rearrangement: An Underexplored Scaffold for Medicinal Chemistry

Angewandte Chemie, EarlyView.
Modular access to underexplored C5‐sulfenyl thiazoles via an intermolecular Pummerer rearrangement is reported. The methodology exhibits a broad functional group tolerance enabling the seamless design of trisubstituted thiazole cores bearing a sulfur handle for further elaboration.
Joe L. Smy, Theo C. Webb, Barnaby W. Greenland, S. Mark Roe, John Spencer, Storm Hassell‐Hart   +5 more
wiley   +2 more sources

Scientific opinion on the renewal of the authorisation of proFagus Smoke R709 (SF‐008) as a smoke flavouring Primary Product

EFSA Journal, 2023
The EFSA Panel on Food Additives and Flavourings (FAF) was requested to evaluate the safety of the smoke flavouring Primary Product proFagus Smoke R709 (SF‐008), for which a renewal application was submitted in accordance with Article 12(1) of Regulation
EFSA Panel name on Food Additives and Flavourings (FAF), Maged Younes, Gabriele Aquilina, Laurence Castle, Gisela Degen, Karl‐Heinz Engel, Paul J Fowler, Maria Jose Frutos Fernandez, Peter Fürst, Ursula Gundert‐Remy, Rainer Gürtler, Trine Husøy, Melania Manco, Peter Moldeus, Sabina Passamonti, Romina Shah, Ine Waalkens‐Berendsen, Matthew Wright, Romualdo Benigni, Polly Boon, Claudia Bolognesi, Eugenia Cordelli, Kevin Chipman, Gisela Degen, Ullrika Sahlin, Maria Carfì, Carla Martino, Agnieszka Mech, Salvatore Multari, Vasantha Palaniappan, Alexandra Tard, Wim Mennes   +31 more
doaj   +1 more source

(Z)-5-(3′,4′-Bis(benzyloxy)benzylidene)furan-2(5H)-one [PDF]

, 2021
Over the years secondary metabolites have been considered as lead molecules both in their natural form and as templates for medicinal chemistry. Some secondary metabolites such as polyphenols and flavan-3-ols exert beneficial effects after a modification
Angelica Artasensi, Giulio Vistoli, Laura Fumagalli, Giovanna Baron, Giancarlo Aldini   +4 more
core   +1 more source

Scientific Opinion on Flavouring Group Evaluation 217 Revision 2 (FGE.217Rev2), consideration of genotoxic potential for α,β‐unsaturated ketones and precursors from chemical subgroup 4.1 of FGE.19: lactones

EFSA Journal, 2019
The Panel on Food Additives and Flavourings of the European Food Safety Authority was requested to evaluate the genotoxic potential of 12 flavouring substances from subgroup 4.1 of FGE.19 in the Flavouring Group Evaluation 217 (FGE.217).
EFSA Panel on Food Additives and Flavourings (FAF), Maged Younes, Gabriele Aquilina, Laurence Castle, Karl‐Heinz Engel, Paul Fowler, Maria Jose Frutos Fernandez, Peter Fürst, Ursula Gundert‐Remy, Rainer Gürtler, Trine Husøy, Peter Moldeus, Agneta Oskarsson, Romina Shah, Ine Waalkens‐Berendsen, Detlef Wölfle, Romualdo Benigni, Claudia Bolognesi, Kevin Chipman, Eugenia Cordelli, Gisela Degen, Daniel Marzin, Camilla Svendsen, Maria Carfì, Giorgia Vianello, Wim Mennes   +25 more
doaj   +1 more source

Competition between ring-puckering and ring-opening excited state reactions exemplified on 5H-furan-2-one and derivatives

, 2020
International audienceThe influence of ring-puckering on the light-induced ring-opening dynamics of heterocyclic compounds was studied on the sample 5-membered ring molecules γ-valerolactone and 5H-furan-2-one using time-resolved photoelectron ...
Joachim Galiana, Schalk, Oliver,, Oliver Schalk, Fdez Galván, Ignacio, Thomas, Richard, Galiana, Joachim,, Morgane Vacher, Schalk, Oliver, Larsson, Tobias L., Tobias L. Larsson, Vacher, Morgane, Hansson, Tony,, Thomas, Richard,, Galvan, Ignacio Fdez., Galiana, Joachim, Larsson, Tobias,, Ting Geng, Fernández Galván, Ignacio,, Larsson, Tobias, Tony Hansson, Vacher, Morgane,, Richard D. Thomas, Geng, Ting,, Thomas, Richard D.,, Hansson, Tony, Geng, Ting, Ignacio Fdez. Galván   +26 more
core   +1 more source