Results 31 to 40 of about 37,838,535 (141)

Utility of 5-(furan-2-yl)-3-(p-tolyl)-4,5-dihydro-1H-pyrazole-1-carbothioamide in the synthesis of heterocyclic compounds with antimicrobial activity

BMC Chemistry, 2019
Background Pyrazolines show different biological activities. In recent years, interest in the chemistry of hydrazonoyl halides has been renewed. 1,3,4-Thiadiazoles are one of the most common heterocyclic pharmacophores with a wide range of biological ...
Abdou O. Abdelhamid, Ibrahim E. El Sayed, Yasser H. Zaki, Ahmed M. Hussein, Mangoud M. Mangoud, Mona A. Hosny   +5 more
doaj   +1 more source

Scientific opinion on the renewal of the authorisation of SmokEz C‐10 (SF‐005) as a smoke flavouring Primary Product

EFSA Journal, 2023
The EFSA Panel on Food Additives and Flavourings (FAF) was requested to evaluate the safety of the smoke flavouring Primary Product SmoKEz C‐10 (SF‐005), for which a renewal application was submitted in accordance with Article 12(1) of Regulation (EC) No
EFSA Panel name on Food Additives and Flavourings (FAF), Maged Younes, Gabriele Aquilina, Laurence Castle, Gisela Degen, Karl‐Heinz Engel, Paul J Fowler, Maria Jose Frutos Fernandez, Peter Fürst, Ursula Gundert‐Remy, Rainer Gürtler, Trine Husøy, Melania Manco, Peter Moldeus, Sabina Passamonti, Romina Shah, Ine Waalkens‐Berendsen, Matthew Wright, Romualdo Benigni, Polly Boon, Claudia Bolognesi, Eugenia Cordelli, Kevin Chipman, Gisela Degen, Ullrika Sahlin, Maria Carfì, Carla Martino, Salvatore Multari, Vasantha Palaniappan, Alexandra Tard, Wim Mennes   +30 more
doaj   +1 more source

Tandem Achmatowicz Rearrangement and Acetalization of 1‑[5-(Hydroxyalkyl)-furan-2-yl]-cyclobutanols Leading to Dispiroacetals and Subsequent Ring-Expansion to Form 6,7-Dihydrobenzofuran-4(5H)‑ones

, 2018
Herein, we report a one-pot protocol for the synthesis of dispiroacetals 4 bearing a cyclobutane motif via tandem Achmatowicz rearrangement and acetalization of 1-[5-(hydroxyalkyl)-furan-2-yl]-cyclobutanols 3 with m-CPBA as the oxidant and AgSbF6 as an ...
Wenkun Luo (5597648), Biaolin Yin (1651651), Hui Peng (116756), Huanfeng Jiang (1392913)   +3 more
core   +3 more sources

Scientific opinion on the renewal of the authorisation of proFagus Smoke R714 (SF‐001) as a smoke flavouring Primary Product

EFSA Journal, 2023
The EFSA Panel on Food Additives and Flavourings (FAF) was requested to evaluate the safety of the smoke flavouring Primary Product proFagus Smoke R714 (SF‐001), for which a renewal application was submitted in accordance with Article 12(1) of Regulation
EFSA Panel name on Food Additives and Flavourings (FAF), Maged Younes, Gabriele Aquilina, Laurence Castle, Gisela Degen, Karl‐Heinz Engel, Paul J Fowler, Maria Jose Frutos Fernandez, Peter Fürst, Ursula Gundert‐Remy, Rainer Gürtler, Trine Husøy, Melania Manco, Peter Moldeus, Sabina Passamonti, Romina Shah, Ine Waalkens‐Berendsen, Matthew Wright, Romualdo Benigni, Polly Boon, Claudia Bolognesi, Eugenia Cordelli, Kevin Chipman, Ullrika Sahlin, Maria Carfì, Blanka Halamoda, Agnieszka Mech, Carla Martino, Salvatore Multari, Vasantha Palaniappan, Alexandra Tard, Wim Mennes   +31 more
doaj   +1 more source

N-[(2S)-4-Chloro-2-(l-menthyloxy)-5-oxo-2,5-dihydro-3-furyl]-l-alanine

Acta Crystallographica Section E, 2009
The title compound, C17H26ClNO5, was prepared via a tandem asymmetric Michael addition–elimination reaction of (5S)-3,4-dichloro-5-(l-menthyloxy)furan-2(5H)-one and l-alanine in the presence of potassium hydroxide.
Kai Yang, Zhao-yang Wang, Xiu-mei Song, Zhao-yang Li   +3 more
doaj   +1 more source

New Approaches for the Synthesis of Heterocyclic Compounds Derived from Cyclohexan-1,3-dione with Anti-proliferative Activities

Acta Chimica Slovenica, 2021
In the present work a series of heterocyclization reactions were adopted using cyclohexan-1,3-dione through its reaction with either furan-2-carbaldehyde or thiophene-2-carbaldehyde to give the corresponding ylidene derivatives 3a,b. The latter compounds
Rafat Milad Mohareb, Yara Raafat Milad, Ayat Ali Masoud   +2 more
doaj   +1 more source

2-(1H-Benzotriazol-1-yl)-1-(furan-2-yl)ethanol

, 2011
In the title compound, C12H11N3O2, the benzotriazole ring system is approximately planar [maximum deviation = 0.008 (1) angstrom] and its mean plane is oriented at a dihedral angle of 24.05 (4)degrees with respect to the furan ring.
Meral Bayraktar, Özden Özel Güven, Güven, Özden Özel, Bayraktar, Meral, Tuncer Hökelek, Tuncer Hökelek, Hökelek,Tuncer, Hökelek, T., Coles, S.J., J. Coles, Simon, Özel Güven, Ö., Simon J. Coles, Bayraktar, M., Özden Özel Güven   +13 more
core   +1 more source

Synthesis and Evaluation of Furan-2(5H)- One Based CCK Antagonists [PDF]

The furan based template, furan-2(5H)-one, is a relatively well known and important structure in nature. The structural arrangement of this template allows it to be susceptible to nucleophilic attack at different sites of this molecule, which can help in
Dunn, S.
core   +1 more source

Chemo-, Regio-, and Stereoselective Assembly of Polysubstituted Furan-2(5H)-ones Enabled by Rh(III)-Catalyzed Domino C–H Alkenylation/Directing Group Migration/Lactonization: A Combined Experimental and Computational Study [PDF]

, 2021
Exploring multistep cascade reactions triggered by C–H activation are recognized as appealing, yet challenging. Herein, we disclose a Rh(III)-catalyzed domino C–H coupling of N-carbamoyl indoles and 4-hydroxy-2-alkynoates for the streamlined assembly of ...
Zhao, Fei, Qiao, Jin, Gong, Xin, Lu, Yangbin, Wu, Xiaowei, Yi, Wei, Lin, Shuang, Zhang, Xiaoning, Liu, Siyu, Zhou, Zhi   +9 more
core   +3 more sources

Unlocking the Alkynyl Bromide Radical Anion With Alternating Current for Inverse Sonogashira C─H Coupling

Advanced Science, EarlyView.
An alternating current (AC)‐promoted, Pd‐catalyzed ortho‐aryl C─H alkynylation of 2,3‐diaryl acrylaldehydes is described. This synthetic scheme accommodates a broad substrate scope, delivering alkynylated stilbene derivatives with excellent arene site selectivity.
Junya Wang, Xiaozhou Wang, Pui Ying Choy, Chi‐Wai Cheung, Li‐Wen Xu, Hung Kay Lee, Gui‐Juan Cheng, Fuk Yee Kwong   +7 more
wiley   +1 more source