Results 151 to 160 of about 2,649 (197)
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An efficient synthesis of furanocoumarins
Tetrahedron, 1992Abstract An efficient synthesis of linear and angular furanocoumarins has been carried out starting from iodoumbelliferone derivatives. First synthesis of 6-iodoumbelliferone is described. The average yields are higher than those reported before.
Eva Zubía +3 more
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Quantitative Recovery of Furanocoumarins fromPsoralea bituminosa
Phytochemical Analysis, 1997The occurrence of bound coumarin derivatives in the Fabaceae has already been demonstrated. In an attempt to determine the yield of furanocoumarins following exhaustive recovery from Psoralea bituminosa, three different hydrolytic procedures have been employed. Method 1 involved the methanolic extraction of plant material followed by acid hydrolysis of
INNOCENTI, GABBRIELLA +4 more
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Furanocoumarins from the root ofAngelica dahurica
Archives of Pharmacal Research, 2000Five furanocoumarins including a new one were isolated from the root of Angelica dahurica by repeated silica gel column chromatography. Their chemical structures were determined to be isoimperatorin (1), oxypeucedanin hydrate-3"-butyl ether (2), imperatorin (3), knidilin (4), and oxypeucedanin hydrate (5).
N I, Baek, E M, Ahn, H Y, Kim, Y D, Park
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Distribution of Furanocoumarins in Grapefruit Juice Fractions
Journal of Agricultural and Food Chemistry, 2005The reported effects of grapefruit (Citrus paradisi Macf.) juice on oral bioavailability of certain prescription drugs have led to the discovery of the inhibition by compounds in grapefruit of cytochrome P450 3A4 (CYP3A4) in the intestinal wall and liver.
John A, Manthey, Béla S, Buslig
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ONE STEP DIMERIZATION OF LINEAR FURANOCOUMARINS
Synthetic Communications, 2002AbstractFor Abstract see ChemInform Abstract in Full Text.
Summon Koul +5 more
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Antigenotoxic activity of naturally occurring furanocoumarins
Environmental and Molecular Mutagenesis, 2011This study was designed to investigate the antigenotoxic effects of a series of naturally occurring furanocoumarins (NOFs) including isoimperatorin, imperatorin, (+)-oxypeucedanin, (+)-byakangelicol, and (+)-byakangelicine on antigenotoxic activities against genotoxicity induced by carcinogens [furylfuramide and N-methyl-N'-nitro-N-nitrosoguanidine ...
Shinsuke, Marumoto +2 more
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The Role of Dihydropsoralen in Furanocoumarin Metabolism
Canadian Journal of Biochemistry, 1973Trapping experiments with [2-14C]umbelliferone and 2′,3′-dihydropsoralen (DHP) administered to Ruta graveolens yielded negative results over metabolic periods of 5–24 h. Specific radioactivities of psoralen were comparable to those previously observed, but those of DHP were about two orders of magnitude lower.
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A furanocoumarin from Dorstenia contrajerva
Phytochemistry, 1991Abstract A new furanocoumarin, 5-[3,4-epoxy-2,7-dimethyl-6,7-octenoyl]psoralen was isolated and identified from Dorstenia contrajerva .
Lee A. Swain +3 more
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Biosynthesis of furanocoumarins in parsnips
Phytochemistry, 1970Abstract Labelling experiments have shown that umbelliferone, and to a lesser degree p -coumaric acid, are precursors of bergapten, imperatorin, isopimpinellin and xanthotoxin in Pastinaca sativa L. C-2 and C-5 of mevalonate, which has been proposed as a precursor of two furan ring carbons and of dimethylallyl substituents, were both incorporated ...
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A Straightforward Entry into Polyketide Monoprenylated Furanocoumarins and Pyranocoumarins
Journal of Natural Products, 1999A regioselective synthesis of 5-methyl- and 5-ethyl-4-hydroxycoumarin (1b and 1c, respectively) is described. Starting from these compounds, several prenylated polyketide coumarins of limited availability from natural sources and important taxonomic relevance were prepared.
APPENDINO, Giovanni Battista +3 more
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