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Antiviral activity of furanocoumarins isolated from Angelica dahurica against influenza a viruses H1N1 and H9N2.

Journal of Ethnopharmacology, 2020
ETHNOPHARMACOLOGICAL RELEVANCE Angelica dahurica (Hoffm.) Benth. & Hook.f. ex Franch. & Sav. (Umbelliferae family) is an herbaceous, perennial plant native to northern and eastern Asia. The root of A.
Ba-Wool Lee   +7 more
semanticscholar   +1 more source

Isopimpinellin, a furanocoumarin

Journal of Crystal and Molecular Structure, 1977
Isopimpinellin (5,8-dimethoxypsoralen), C13H10O5, is a furanocoumarin isolated from the leaves and stems ofA pium australe Thouars. (Umbelliferae) collected near Concepcion, Chile. Extracts of the plant show activity against P-388 lymphocytic leukemia.
E. M. Gop�lakrishna   +3 more
openaire   +1 more source

O-methyltransferases of furanocoumarin biosynthesis

Archives of Biochemistry and Biophysics, 1978
Extracts of the furanocoumarin-synthesizing plants, Ruta graveolens L. and Heracleum lanatum Michx., contain a soluble O-methyltransferase system mediating the methylation of the 5- and 8-hydroxyls of linear furanocoumarins by S-adenosyl- l -methionine.
H J, Thompson, S K, Sharma, S A, Brown
openaire   +2 more sources

Three types of enzymes complete the furanocoumarins core skeleton biosynthesis in Angelica sinensis.

Phytochemistry
Furanocoumarins (FCs) are widely distributed secondary metabolites found in higher plants, including Apiaceae, Rutaceae, Moraceae, and Fabaceae. They play a crucial role in the physiological functions of plants and are well-known for their diverse ...
Kaixuan Wang   +11 more
semanticscholar   +1 more source

Furanocoumarins from Heracleum canescens

Phytochemistry, 1982
Abstract The ethanolic extract of the fresh roots of Heracleum canescens has afforded, besides sitosterol, osthol, methyl 3,4,5-trimethoxybenzoate and 11 furanocoumarins.
S Harkar
exaly   +2 more sources

Furanocoumarins promote proteasomal degradation of viral HBx protein and down-regulate cccDNA transcription and replication of hepatitis B virus.

Virology
Nucleot(s)ide analogues, the current antiviral treatments against chronic hepatitis B (CHB) infection, are non-curative due to their inability to eliminate covalently closed circular DNA (cccDNA) from the infected hepatocytes.
Purnima Tyagi   +7 more
semanticscholar   +1 more source

An efficient synthesis of furanocoumarins

Tetrahedron, 1992
Abstract An efficient synthesis of linear and angular furanocoumarins has been carried out starting from iodoumbelliferone derivatives. First synthesis of 6-iodoumbelliferone is described. The average yields are higher than those reported before.
Eva Zubía   +3 more
openaire   +1 more source

Inhibitory potential of furanocoumarins against cyclin dependent kinase 4 using integrated docking, molecular dynamics and ONIOM methods

Journal of Biomolecular Structure and Dynamics
Cyclin Dependent Kinase 4 (CDK4) is vital in the process of cell-cycle and serves as a G1 phase checkpoint in cell division. Selective antagonists of CDK4 which are in use as clinical chemotherapeutics cause various side-effects in patients ...
Srutishree Sarma   +4 more
semanticscholar   +1 more source

Sustainable and efficient surfactant-based microwave-assisted extraction of target polyphenols and furanocoumarins from fig (Ficus carica L.) leaves

, 2020
Nowadays, developed an efficient and sustainable method to extract bioactive compounds from plants biomass has gained more and more attention. As surfactant aqueous possesses an obviously advantage of highly extraction efficiency from the raw plants, it ...
Liang Yu   +7 more
semanticscholar   +1 more source

Determination of citrus juice coumarins, furanocoumarins and methoxylated flavones using solid phase extraction and HPLC with photodiode array and fluorescence detection.

Food Chemistry, 2019
A synergistic combination of analytical techniques was developed for the simultaneous determination of the three most biologically active chemical families in citrus juices: methoxylated flavones, coumarins, and furanocoumarins.
Guijie Li   +4 more
semanticscholar   +1 more source

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