Results 31 to 40 of about 620,439 (167)

Reactions of 5-(4-methoxy-3-methylphenyl)-2(3H)-furanone with some electrophilic and nucleophilic reagents [PDF]

, 2017
5-(4-Methoxy-3-methylphenyl)-2(3H)-furanone was prepared and reacted with some nucleophilic and electrophilic reagents. The condensation of furanone with aromatic aldehydes or phthalic anhydride yielded the corresponding 3-arylidenefuranone derivatives ...
Mohamed Helmy Abd El-hamied Soliman, El-Sakka, Sahar Said Ahmed, Sahar Said Ahmed El-Sakka, Soliman, Mohamed Helmy Abd El-hamied   +3 more
core   +1 more source

Synthesis and antitumor activity evaluation of some N-heterocycles derived from pyrazolyl-substituted 2(3H)-furanone

, 2016
Pyrazolyl-substituted 2(3H)-furanone was allowed to react with different nitrogen nucleophiles such as hydrazine hydrate, ethylenediamine, ethanolamine, and anthranilic acid to give pyrrolone and benzoxazinone derivatives.
Sayed K. Ramadan (2813593), Magdy I. Elzahar (2878217), Wael S. I. Abou-Elmagd (723053), Ahmed K. EL-Ziaty (2813590), Ahmed I. Hashem (2813584)   +4 more
core   +1 more source

Anti-Pathogenic Properties of the Combination of a T3SS Inhibitory Halogenated Pyrrolidone with C-30 Furanone

Molecules, 2021
Antimicrobial resistance is one of the current public health challenges to be solved. The World Health Organization (WHO) has urgently called for the development of strategies to expand the increasingly limited antimicrobial arsenal.
Nelly Araceli Aburto-Rodríguez, Naybi Muñoz-Cázares, Víctor Alberto Castro-Torres, Bertha González-Pedrajo, Miguel Díaz-Guerrero, Rodolfo García-Contreras, Héctor Quezada, Israel Castillo-Juárez, Mariano Martínez-Vázquez   +8 more
doaj   +1 more source

Stereoselective Triplet‐Sensitised Radical Reactions of Furanone Derivatives

, 2010
International audienceAbstract The stereo‐ and regioselectivity of triplet‐sensitised radical reactions of furanone derivatives have been investigated.
Gassama, Abdoulaye, Bulach, Véronique, Martinez, Agathe, Jahjah, Rabih, Suzuki, Chikako, Abe, Manabu, Hoffmann, Norbert, Nuzillard, Jean‐marc   +7 more
core   +1 more source

2,5-Dimethoxy-2,5-dihydrofuran chemistry: a new approach to 2(5H)-furanone derivatives

, 2008
2,5-Dimethoxy-2,5-dihydrofuran is a synthetic equivalent of 2(5H)-furanone or 2-trimethylsilyloxyfuran, useful C(4) synthons in the preparation of 5-substituted-2(5H)-furanone derivatives. The reaction conditions adopted allow to obtain different classes
SAMARITANI, SIMONA, Malanga C., MALANGA, CORRADO, GARZELLI R   +3 more
core   +1 more source

Synthetic Strategies for the Construction of Cyclobutane‐Fused Heterocycles

European Journal of Organic Chemistry, EarlyView.
Cyclobutane‐fused heterocycles are important motifs commonly present in bioactive compounds, recognized for their rigid 3D structures that confer unique properties. However, synthesizing these compounds remains challenging. This review discusses current methods for their synthesis, such as photochemical, metal‐catalyzed, and Lewis acid‐mediated [2 + 2]
Michela Vargiu, Mauro Uras, Angelo Frongia   +2 more
wiley   +1 more source

Immobilized furanone derivatives as inhibitors for adhesion of bacteria on modified poly(styrene-co-maleic) anhydride)

, 2012
The ability of brominated furanones and other furanone compounds with 2(3H) and 2(5H) cores to inhibit bacterial adhesion of surfaces as well deactivate (destroy) them has been previously reported.
Klumperman, L., Bshena, O., Cloete, T.E., Gule, N.P., Kwaadsteniet, de, M.   +4 more
core   +1 more source

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

Scientific Opinion on Flavouring Group Evaluation 99 Revision 1 (FGE.99Rev1): Consideration of furanone derivatives evaluated by the JECFA (63rd, 65th and 69th meetings)

EFSA Journal, 2015
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) of the European Food Safety Authority was requested to consider evaluations of flavouring substances assessed since 2000 by the Joint FAO/WHO Expert Committee on Food ...
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj   +1 more source

Scientific Opinion on Flavouring Group Evaluation 99 (FGE.99): Consideration of furanone derivatives evaluated by the JECFA (63^rd, 65^th and 69^th meetings) [PDF]

EFSA Journal, 2012
<p>The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to consider evaluations of flavouring substances assessed since 2000 by the Joint FAO/WHO Expert Committee on Food ...
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj   +1 more source