Results 21 to 30 of about 2,598 (200)

Computational Studies of Furanone and its 5Methyl/5Phenyl Derivatives [PDF]

Advanced Journal of Chemistry, Section B, 2020
The properties for 2(5H)-furanone and 2(5Methyl)- and 2(5Phenyl)-furanone derivatives have been explored by computational chemistry approach. The subatomic unit calculations have been done to optimize the models and to evaluate their corresponding properties, in which several achievements have been seen for the investigated models. The energy levels of
Nikoo Ghanbari, Homa Azizian, Mahmoud Mirzaei   +2 more
openaire   +1 more source

Utility of novel 2-furanones in synthesis of other heterocyclic compounds having anti-inflammatory activity with dual COX2/LOX inhibition

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Inflammation is associated with the development of several diseases comprising cancer and cardiovascular disease. Agents that suppress cyclooxygenase (COX) and lipoxygenase (LOX) enzymes, besides chemokines have been suggested to minimise inflammation ...
Rania H. Abd El-Hameed, Shahenda Mahgoub, Hend M. El-Shanbaky, Mosaad S. Mohamed, Sahar A. Ali   +4 more
doaj   +1 more source

Synthesis of New Representatives of Push–Pull Enamines 5-Aryl-3-((dimethylamino)methylene)furan-2(3H)-Ones

Chemistry Proceedings, 2023
The conditions for the synthesis of dimethylaminomethylene derivatives were selected based on the interaction of arylfuran-2(3H)-ones and dimethylformamide dimethylacetal (DMA-DMF), proceeding through the methylene active unit of the furanone ring.
Alexandra S. Tikhomolova, Zhanna V. Mamleeva, Alevtina Yu. Yegorova   +2 more
doaj   +1 more source

Two new furanone derivatives from the endophytic fungus Byssochlamys sp. and their cytotoxic activities

, 2023
Two new furanone derivatives, byssochlanones A–B (1–2) were purified from the endophytic fungus Byssochlamys sp. isolated from the wetland plant, Phragmites australis.
Fan-Wei Liu (7473446), Ying Chen (9697), Jie Wang (16762), Li-Na Guo (1490104), Wen-Bin Gao (6914912), Qi Liu (33068), Jin Ye (251091), Bo Song (255492), Wei Dong (6479), Cai-Lin Zhao (14127588)   +9 more
core   +1 more source

Electronic Smoking Devices Among University Students: Usage Patterns and Chemical Composition of Inhaled Substances. [PDF]

Anal Sci Adv
ABSTRACT This study investigated the prevalence of electronic smoking device (ESD) use and its associated behavioural and chemical risks among university students in Bahia, Brazil. A cross‐sectional survey was conducted with 355 students from public and private institutions through an online questionnaire between April and May 2023. Among participants,
Valenzuela EF, Almeida RSS, Simões IF, Gonçalves Miranda A, Ramos MO, Maciel RRBT, Rosa FW, de Freitas Santos Júnior A.   +7 more
europepmc   +2 more sources

Arylation of β,γ-unsaturated lactones by a Heck-Matsuda reaction: an unexpected route to aryldiazene butenolides and pyridazinones

Química Nova, 2010
The palladium catalysed coupling of aryldiazonium salts with β-γ-unsaturated lactones under basic conditions has been investigated. Both (3H)-furanone and α-angelicalactone were evaluated as substrates in the Heck Matsuda reaction but both
Jason G. Taylor, Carlos Roque D. Correia
doaj   +1 more source

Polyketide Derivatives from the Endophytic Fungus Phaeosphaeria sp. LF5 Isolated from Huperzia serrata and Their Acetylcholinesterase Inhibitory Activities

Journal of Fungi, 2022
The secondary metabolites of Phaeosphaeria sp. LF5, an endophytic fungus with acetylcholinesterase (AChE) inhibitory activity isolated from Huperzia serrata, were investigated.
Yiwen Xiao, Weizhong Liang, Zhibin Zhang, Ya Wang, Shanshan Zhang, Jiantao Liu, Jun Chang, Changjiu Ji, Du Zhu   +8 more
doaj   +1 more source

Convenient Synthesis of 3,4-Dichloro-5-hydroxy-2(5H)-Furanone Glycoconjugates

Molecules, 2011
3,4-Dichloro-5-hydroxy-2(5H)-furanone treated with methyl chloroformate in the presence of diisopropylethylamine (Hünig’s base) gave the corresponding carbonate. The labile methoxycarbonyloxy group smoothly undergoes substitution by amino alcohols.
Edyta Gondela, Krzysztof Z. Walczak
doaj   +1 more source

Side-chain Modifications of Highly Functionalized 3(2H)-Furanones

Molecules, 2012
A series of 3(2H)-furanones, based on side-chain modifications of a parent 3(2H)-furanone, was synthesized in good yield. The parent compound was prepared by hydrogenolysis, and subsequent acid hydrolysis, of isoxazole derivatives.
Gil Valdo José da Silva, Maurício Gomes Constantino, Viviani Nardini, Shirley Muniz Machado Rodrigues   +3 more
doaj   +1 more source

THE SYNTHESIS OF (5-HYDROXY-5-(1-METHOXYPROPAN-2-YL) -4-METHYLFURAN-2(5H)-ONE, 5-(1-METHOXYPROPAN-2-YL) -4-METHYLFURAN-2(5H)-ONE) AND BIOLOGICAL ACTIVITY

Journal of Fundamental and Applied Sciences, 2015
Butenolides are a class of lactones with a four carbon heterocyclic ring structure.  They are sometimes considered as oxidized derivatives of furan. The simplest butenolide is 2-furanone, which is a common component of larger natural products and is ...
N. Gherraf, N. Tamma
doaj   +1 more source