Molecular characterization and inhibition of cyclic-di-GMP receptor proteins in Pseudomonas aeruginosa: INSIGHTS from docking and dynamics studies [PDF]
Biochemistry and Biophysics ReportsThe emergence of antibiotic-resistant Pseudomonas aeruginosa biofilms necessitates novel therapeutic strategies targeting virulence pathways. In this study the structural mechanisms underlying the differential anti-biofilm efficacy of epigallocatechin ...
Sinethemba H. Yakobi +2 more
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3,4-Dihalo-5-hydroxy-2(5H)-furanones: Highly Reactive Small Molecules [PDF]
Molecules3,4-Dichloro-5-hydroxy-2(5H)-furanone and its dibromo analog are highly reactive molecules. Both are members of the 2(5H)-furanone family, which are important as pharmacophores present in drugs and natural products.
Katarzyna Żurawska +3 more
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Evaluation of Potential Genotoxicity of New Furanone Derivatives – QS Inhibitors [PDF]
Учёные записки Казанского университета: Серия Естественные науки, 2017 Quorum sensing (QS) is a regulatory mechanism by which bacteria coordinate the expression of certain genes in response to their population density by producing, releasing and detecting small signal molecules.
E.V. Babynin +2 more
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Integrating E-senses and volatile fingerprinting to decipher type-specific flavor signatures in four commercial Huangjiu [PDF]
Food Chemistry: XThis study established an integrated strategy to characterize the flavor profiles of four commercial Huangjiu types (dry, semi-dry, semi-sweet, and sweet). Electronic tongue (E-tongue) analysis showed that sweet Huangjiu exhibited the strongest sourness,
Zhenni Qu +9 more
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Volatile aroma profiles and associated microbiota of Yunnan Shiping sour-pulp-fermented stinky tofu [PDF]
Food Chemistry: XYunnan Shiping stinky tofu is a traditional sour-pulp-fermented soybean product with distinctive volatile aroma characteristics. In this study, headspace solid-phase microextraction-gas chromatography–mass spectrometry (HS-SPME-GC–MS), relative odor ...
Yanhui Xu +9 more
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(-)-Epi-Osmundalactone-Rich Fraction from Angiopteris evecta Suppresses Proliferation and Induces Intrinsic Apoptosis in Non-Small Cell Lung Cancer Cells via MAPK Pathway Modulation [PDF]
PlantsNon-small cell lung cancers (NSCLCs), most notably adenocarcinoma and large cell carcinoma, have been the most frequently diagnosed lung cancer and continue to represent a leading cause of cancer-related mortality worldwide, largely due to its aggressive
Punnida Arjsri +6 more
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Melifoliox B, a novel phloroglucin derivative isolated from Melicope barbigera (Rutaceae) and synthesis of new oxidation products from melifoliones A and B [PDF]
Beilstein Journal of Organic ChemistryIn addition to new acetophenones and 2H-chromenes, the dichlormethane extract from leaves of Melicope barbigera A. Gray (Rutaceae) afforded a mixture of the isomeric melifoliones A (1) and B (2) as well as an oxidation product of 2, whose structure was ...
Horst Weber +7 more
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Temporal dynamics of ruminal metabolome and fermentation in response to molasses-treated Guinea grass–cowpea silage [PDF]
Veterinary and Animal ScienceMolasses is widely used to improve silage quality, but little is known about how its inclusion during the ensiling of tropical forages affects ruminal degradability kinetics and metabolomic responses upon subsequent microbial fermentation.
Armess Prince Gynth Sossou +1 more
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, 2023 Two new furanone derivatives, byssochlanones A–B (1–2) were purified from the endophytic fungus Byssochlamys sp. isolated from the wetland plant, Phragmites australis.
Fan-Wei Liu (7473446) +9 more
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Química Nova, 2010 The palladium catalysed coupling of aryldiazonium salts with β-γ-unsaturated lactones under basic conditions has been investigated. Both (3H)-furanone and α-angelicalactone were evaluated as substrates in the Heck Matsuda reaction but both
Jason G. Taylor, Carlos Roque D. Correia
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