Results 1 to 10 of about 2,270 (149)

Furanone Derivatives from Terrestrial spp [PDF]

Natural Product Communications, 2012
Chemical investigation of the terrestrial Streptomyces sp. isolates GT2005/020 and ANK148 led to the isolation of two microbial furanone derivatives, 5-hydroxy-4-methylnaphtho[1,2-b]furan-3-one (1) and 4-hydroxy-5-methyl-furan-3-one (2), respectively ...
Muhammad Arfan, Khaled A. Shaaban, Anja Schüffler, Hartmut Laatsch   +3 more
doaj   +4 more sources

Molecular characterization and inhibition of cyclic-di-GMP receptor proteins in Pseudomonas aeruginosa: INSIGHTS from docking and dynamics studies [PDF]

Biochemistry and Biophysics Reports
The emergence of antibiotic-resistant Pseudomonas aeruginosa biofilms necessitates novel therapeutic strategies targeting virulence pathways. In this study the structural mechanisms underlying the differential anti-biofilm efficacy of epigallocatechin ...
Sinethemba H. Yakobi, Winnie Ramaloko, Nontuthuko E. Maningi   +2 more
doaj   +2 more sources

3,4-Dihalo-5-hydroxy-2(5H)-furanones: Highly Reactive Small Molecules [PDF]

Molecules
3,4-Dichloro-5-hydroxy-2(5H)-furanone and its dibromo analog are highly reactive molecules. Both are members of the 2(5H)-furanone family, which are important as pharmacophores present in drugs and natural products.
Katarzyna Żurawska, Anna Byczek-Wyrostek, Anna Kasprzycka, Krzysztof Walczak   +3 more
doaj   +2 more sources

Furanones and Anthranilic Acid Derivatives from the Endophytic Fungus Dendrothyrium variisporum [PDF]

Molecules, 2017
Extracts from an endophytic fungus isolated from the roots of the Algerian plant Globularia alypum showed prominent antimicrobial activity in a screening for novel antibiotics. The producer organism was identified as Dendrothyrium variisporum by means of
Rémy B. Teponno, Sara R. Noumeur, Soleiman E. Helaly, Stephan Hüttel, Daoud Harzallah, Marc Stadler   +5 more
doaj   +4 more sources

QSAR analysis of furanone derivatives as potential COX-2 inhibitors: kNN MFA approach

Journal of Saudi Chemical Society, 2014
A series of thirty-two furanone derivatives with their cyclooxygenase-2 inhibitory activity were subjected to quantitative structural–activity relationship analysis to derive a correlation between biological activity as a dependent variable and various ...
Ruchi Bhatiya, Ankur Vaidya, Sushil K. Kashaw, Abhishek K. Jain, Ram K. Agrawal   +4 more
doaj   +3 more sources

Scientific Opinion on Flavouring Group Evaluation 99 Revision 1 (FGE.99Rev1): Consideration of furanone derivatives evaluated by the JECFA (63rd, 65th and 69th meetings) [PDF]

EFSA Journal, 2015
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) of the European Food Safety Authority was requested to consider evaluations of flavouring substances assessed since 2000 by the Joint FAO/WHO Expert Committee on Food ...
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj   +2 more sources

Melifoliox B, a novel phloroglucin derivative isolated from Melicope barbigera (Rutaceae) and synthesis of new oxidation products from melifoliones A and B [PDF]

Beilstein Journal of Organic Chemistry
In addition to new acetophenones and 2H-chromenes, the dichlormethane extract from leaves of Melicope barbigera A. Gray (Rutaceae) afforded a mixture of the isomeric melifoliones A (1) and B (2) as well as an oxidation product of 2, whose structure was ...
Horst Weber, Kim-Thao Tran-Cong, Bernhard Mayer, Guido J. Reiss, Iryna S. Konovalova, Marc S. Appelhans, Kenneth R. Wood, Claus M. Passreiter   +7 more
doaj   +2 more sources

Evaluation of Potential Genotoxicity of New Furanone Derivatives – QS Inhibitors [PDF]

Учёные записки Казанского университета: Серия Естественные науки, 2017
Quorum sensing (QS) is a regulatory mechanism by which bacteria coordinate the expression of certain genes in response to their population density by producing, releasing and detecting small signal molecules.
E.V. Babynin, R.M. Glazkova, A.R. Kurbangalieva   +2 more
doaj   +1 more source

The nonvolatile and volatile substances changes based on non-target metabonomics reveals the formation mechanism of Tsamba flavor before and after roasting of highland barley [PDF]

Food Chemistry: X
As the traditional staple food for Tibetan people in northwest China, Tsamba is the main processing product of highland barley and roasting is the key processing step to determine the flavor of Tsamba.
Fang Wang, Yin-hua Ma, Hui-yang Xiong, Rui-jun Duan   +3 more
doaj   +2 more sources

The Novel Chiral 2(5H)-Furanone Sulfones Possessing Terpene Moiety: Synthesis and Biological Activity

Molecules, 2023
Over the past decades, 2(5H)-furanone derivatives have been extensively studied because of their promising ability to prevent the biofilm formation by various pathogenic bacteria.
Alsu M. Khabibrakhmanova, Roza G. Faizova, Olga A. Lodochnikova, Regina R. Zamalieva, Liliya Z. Latypova, Elena Y. Trizna, Andrey G. Porfiryev, Katsunori Tanaka, Oskar A. Sachenkov, Airat R. Kayumov, Almira R. Kurbangalieva   +10 more
doaj   +1 more source