Naphthyl‐Based Chalcone Derivatives: A Multifaceted Player in Medicinal Chemistry
ChemistrySelect, Volume 9, Issue 19, May 21, 2024.This review insights the pharmacological activity of naphthyl substituted chalcone derivatives. The anticancer and antibacterial activities were more explored than other activities. The presence of methoxy and naphthyl moiety enhanced the anticancer activity. The antibacterial activity was increased by electron withdrawing groups.
Priyanka Mahesha, Nitinkumar S. Shetty
wiley +1 more source
Oridonin from Rabdosia rubescens: An emerging potential in cancer therapy – A comprehensive review
Food Science &Nutrition, Volume 12, Issue 5, Page 3046-3067, May 2024.Oridonin (ORI), an ent‐kaurane diterpenoid, naturally found in the leaves of Rabdosia rubescens species, has been found to have antitumor and antiangiogenic properties. It inhibits several cancer‐signaling pathways like NFκB, PI3K, BCL2, BCLX, and p53‐mediated pathways.
Muhammad Asif Ali +14 more
wiley +1 more source
Efficient synthesis of fluoroalkylated 1,4,2-oxathiazoles via regioselective [3 + 2]-cycloaddition of fluorinated nitrile oxides with thioketones [PDF]
, 2017 Fluorinated acetonitrile oxides, generated from the corresponding hydroximoyl bromides in the presence of aryl, hetaryl, ferrocenyl, and cycloaliphatic thioketones, undergo efficient [3 + 2]-cycloadditions to give 3- fluoroalkylated 1,4,2-oxathiazoles in
Obijalska, Emilia +3 more
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Analysis of degradation products in thermally treated TATB
Propellants, Explosives, Pyrotechnics, Volume 49, Issue 2, February 2024.Abstract Delineating the chemical composition of TATB (1,3,5‐triamino‐2,4,6‐trinitrobenzene) residues produced from the exposure to abnormal thermal environments should lead to a better understanding of the decomposition paths. Identifying and quantifying each compound in thermally produced residues, monitors which compounds are degrading or forming ...
Keith R. Coffee +7 more
wiley +1 more source
, 2000 A convenient method for the synthesis of 1,2,5-oxadiazole-N-oxides (furoxans) from alfa-nitro-ketoximes, using acidic alumina as catalyst, is ...
MARCOTULLIO M. C. +5 more
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"Nitric Oxide Donors for Biomedical Applications: A Themed Issue Dedicated to Professor Alberto Gasco": Special Issue Editorial Overview. [PDF]
Molecules, 2023 Sodano F, Gazzano E, Fruttero R.
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LUMO maps allow identification of electrophilic centers.
, 2012 LUMO mapped onto a bond surface for studied compounds: a. furoxans, b. benzofuroxans. Blue areas correspond to regions in which the molecule is most susceptible to nucleophilic attack in active compounds the nitrogen of N-oxide moieties.
Paola Hernández (169378) +13 more
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, 2017 © 2017 American Chemical Society. The use of nitric oxide (NO) as a signal for biofilm dispersal has been shown to increase the susceptibility of many biofilms to antibiotics, promoting their eradication. The delivery of NO to biofilms can be achieved by
Poh, WH +13 more
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Enhanced Energetic Performance via the Combination of Furoxan and Oxa-[5,5]bicyclic Structures. [PDF]
Int J Mol Sci, 2023 Zhang Q, Zhang X, Pang S, He C.
europepmc +1 more source
Synthesis, Optimization, and Evaluation of Thiophilic Peptidomimetics as Novel AD Therapies
, 2012 Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that threatens to reach epidemic proportions in the near future. Current AD therapies provide temporary symptomatic relief, but eventually become ineffective due to the presence of ...
Isaac T. Schiefer (1335351)
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