Results 11 to 20 of about 1,568 (180)

Skeletally Tunable Seven-Membered-Ring Fused Pyrroles [PDF]

Organic Letters, 2021
We describe a copper-mediated method that enables the synthesis of seven-membered-ring fused pyrroles (7-mrFPs). The protocol proceeds via an in situ spiro-intermediate ring expansion and tolerates a library of 7-mrFP derivatives with a broad range of functional groups in a simple step with tangible parameters and substrate adaptations.
Dimitrios Andreou, Nsikak B. Essien, Cristina Pubill-Ulldemolins, Michael A. Terzidis, Athanasios N. Papadopoulos, George E. Kostakis, Ioannis N. Lykakis   +6 more
openaire   +2 more sources

S,N-Heteropentacenes – Syntheses of Electron-Rich Anellated Pentacycles

Organic Materials, 2021
This review summarizes syntheses of S,N-heteropentacenes, i.e. electron-rich sulfur and nitrogen-embedding pentacycles, and briefly highlights selected applications in molecular electronics. Depending on the anellation mode and the number of incorporated
Henning R. V. Berens, Thomas J. J. Müller   +1 more
doaj   +1 more source

Diverse Synthesis of Fused Polyheterocyclic Compounds via [3 + 2] Cycloaddition of In Situ-Generated Heteroaromatic N-Ylides and Electron-Deficient Olefins

Molecules, 2023
[3 + 2] Cycloaddition reactions of heteroaromatic N-ylides with electron-deficient olefins have been developed. The heteroaromatic N-ylides, in situ generated from N-phenacylbenzothiazolium bromides, can smoothly react with maleimides under very mild ...
Zhen-Hua Wang, Tong Zhang, Li-Wen Shen, Xiu Yang, Yan-Ping Zhang, Yong You, Jian-Qiang Zhao, Wei-Cheng Yuan   +7 more
doaj   +1 more source

Chiral counteranion controlled chemoselectivity in gold catalysed hydroamination/enantioselective formal 1,3-allylic alcohol isomerisation of β-amino-1,4-enynols

Tetrahedron Chem, 2023
A synthetic method for the preparation of 1,8-dihydroindeno[2,1-b]pyrroles and pyrrol-2-yl methanols in an enantioselective manner that relies on the chiral gold(I)-catalysed reactions of β-amino-1,4-enynols is described.
Lorenzo Carli, Anyawan Tapdara, Jianwen Jin, Yichao Zhao, Philip Wai Hong Chan   +4 more
doaj   +1 more source

Synthesis and Characterization of Peralkylated Pyrrole-Fused Azacoronene

The Journal of Organic Chemistry, 2021
A hexapyrrolohexaazacoronene (HPHAC) with 12 less-bulky peripheral ethyl groups than its aryl-containing HPHAC counterpart was synthesized to investigate the innate character of HPHAC. X-ray diffraction analysis revealed that HPHAC had a planar structure and close packing because of CH-π interactions between the alkyl groups and the HPHAC core ...
Kosuke Oki, Masayoshi Takase, Nagao Kobayashi, Hidemitsu Uno   +3 more
openaire   +3 more sources

Synthesis and Properties of NitroHPHAC: The First Example of Substitution Reaction on HPHAC

Molecules, 2020
Hexapyrrolohexaazacoronene (HPHAC) is one of the N-containing polycyclic aromatic hydrocarbons in which six pyrroles are fused circularly around a benzene.
Yoshiki Sasaki, Masayoshi Takase, Shigeki Mori, Hidemitsu Uno   +3 more
doaj   +1 more source

A Facile Route to N‐Fused Pyrrole Lactams. [PDF]

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Zhi Yang, Decai Fu, Ruimin Shao, Shoufang Zhang   +3 more
openaire   +2 more sources

Remarkable Iodine-Catalyzed Synthesis of Novel Pyrrole- Bearing N-Polyaromatic β-Lactams

Molecules, 2010
Because of their interesting biological properties various methods for the synthesis of substituted pyrroles are described in the literature. However, synthesis of pyrroles fused with a β-lactam ring has not been reported.
Bimal K. Banik, Hector Aguilar, Isabel Salinas, Gildardo Rivera, Debasish Bandyopadhyay   +4 more
doaj   +1 more source

Design, synthesis and molecular docking of new fused 1H-pyrroles, pyrrolo[3,2-d]pyrimidines and pyrrolo[3,2-e][1, 4]diazepine derivatives as potent EGFR/CDK2 inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
A new series of 1H-pyrrole (6a–c, 8a–c), pyrrolo[3,2-d]pyrimidines (9a–c) and pyrrolo[3,2-e][1, 4]diazepines (11a–c) were designed and synthesised. These compounds were designed to have the essential pharmacophoric features of EGFR Inhibitors, they have ...
Amany Belal, Nagwa M. Abdel Gawad, Ahmed B. M. Mehany, Mohammed A. S. Abourehab, Hazem Elkady, Ahmed A. Al‐Karmalawy, Ahmed S. Ismael   +6 more
doaj   +1 more source

Convenient Access to Ferrocene Fused aza-Heterocycles via the Intramolecular Ritter Reaction: Synthesis of Novel Racemic Planar-Chiral 3,4-Dihydroferroceno[c]pyridines and 1H-Ferroceno[c]pyrroles

Inorganics, 2022
An efficient and easy approach to the synthesis of novel racemic planar-chiral 3,4-dihydroferroceno[c]pyridines and 1H-ferroceno[c]pyrroles via the intramolecular Ritter reaction of 2-ferrocenyl-3,3-dimethylbutan-2-ol with nitriles and thiocyanates in ...
Yuliya S. Rozhkova, Irina V. Plekhanova, Alexey A. Gorbunov, Yurii V. Shklyaev   +3 more
doaj   +1 more source