Results 191 to 200 of about 749,719 (265)

Recombinant G-CSF-ApoAI Fusion Protein Is a Pleiotropic Factor. [PDF]

Molecules
Miroshnichenko S, Pykhtina M, Mosalev K, Beklemishev A, Beklemishev A.   +4 more
europepmc   +1 more source

Extending Service Beyond Active Duty: Generalizability of Rheumatoid Arthritis Research Conducted Among US Veterans

Arthritis Care &Research, EarlyView.
Biomedical research involving US veterans continues to advance health care beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both veteran ...
Austin M. Wheeler, Joshua F. Baker, Jennifer L. Barton, Maria I. Danila, Tate M. Johnson, Kamini Kuchinad, Kaleb Michaud, Amir A. Razmjou, J. Steuart Richards, Namrata Singh, Isaac D. Smith, Katherine D. Wysham, Grant W. Cannon, Bryant R. England, Amy Joseph, Deana Lazaro, Katherine P. Liao, Courtney Loecker, Andreas Reimold, Beth I. Wallace, Ted R. Mikuls   +20 more
wiley   +1 more source

Vitronectin-GM-CSF fusion protein hydrogel with a recruitment-anchoring-activation strategy accelerates vascularized tissue regeneration. [PDF]

Regen Biomater
Zhang J, Xia Y, Peng X, Li W, Zhao Y, Chen F, Chen Z.   +6 more
europepmc   +1 more source

M5542, a bifunctional fusion protein targeting CD80, CD86, and OX40L that modulates excessive T-cell activity: a preclinical proof-of-concept study. [PDF]

Front Immunol
Downing M, Christiaansen A, Zhang L, Roe K, Kumar N, Deshpande A, Zhang H, Tarcic O, Toister-Achituv M, Soloviev M, Gross AW, Chen G, Sun CC.   +12 more
europepmc   +1 more source

Structural basis for childhood antibody recognition of the human metapneumovirus fusion protein. [PDF]

Nat Commun
Khalil AM, Ghazi Esfahani B, Miller RJ, Huang J, Kuan G, Balmaseda A, Gordon A, Mousa JJ.   +7 more
europepmc   +1 more source

A novel fusion protein reduces kidney complement in experimental C3 glomerulopathy. [PDF]

Clin Exp Immunol
Malik TH, Kwiatkowska K, Lomax-Browne HJ, Bottomley CM, Bright M, Tean ZS, Akturk AK, Alexander IE, Logan GJ, Pickering MC.   +9 more
europepmc   +1 more source

An Engineered Multifunctional Fusion Protein Targeting Aβ Oligomers, Microglia and Autophagy Ameliorates Cognitive Deficits and Amyloid Pathology in Alzheimer's Disease Mice. [PDF]

Cell Mol Neurobiol
Zhu J, Huang YR, Chen F, Wang MQ, Yu XL, Zhang GF, Liu RT.   +6 more
europepmc   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

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Therapeutic Fusion Proteins

The AAPS Journal, 2023
Therapeutic fusion proteins are a class of hybrid constructs that combine distinct biomolecules into a single platform with the additive effects of the components. The ability to fuse two unrelated proteins provides a means to localize mechanisms to better treat a range of diseases. Fusion proteins can be designed to impart diverse functions, including
Morgan C. Marsh, Shawn C. Owen
openaire   +2 more sources

Fusion proteins in biotechnology

Current Opinion in Biotechnology, 1992
Gene fusion techniques allow the production of recombinant proteins featuring the combined characteristics of the parental products. Originally, these techniques were used to probe transcriptional and translational activity, to translocate proteins across cell membranes, and to facilitate the recovery of proteins.
M, Uhlén, G, Forsberg, T, Moks, M, Hartmanis, B, Nilsson   +4 more
openaire   +2 more sources