Results 211 to 220 of about 7,541,115 (355)

Mechanism of membrane fusion induced by vesicular stomatitis virus G protein

Proceedings of the National Academy of Sciences of the United States of America, 2016
I. Kim, S. Jenni, M. Stanifer, Eatai Roth, S. Whelan, Antoine M. van Oijen, S. Harrison   +6 more
semanticscholar   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Site-Specific Mitochondrial RNA N1-Methyladenosine Demethylation via an Engineered MTS-PUF-ALKBH3 Fusion Protein. [PDF]

Adv Sci (Weinh)
Li X, Kong D, Liu H, Yang J, Zhou J, Qian Y, Zhao D, Li J, Wu X, Zhang T, Sun X, Han Y, Lai L, Li Z.   +13 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Pretargeted Anti-CD20 Radioimmunotherapy with scFv Fusion Protein Safely Combines with BEAM and ASCT in Patients with High-risk B-cell Lymphomas. [PDF]

Mol Cancer Ther
Orozco JJ, Matesan MC, Lundberg SJ, Haaf RL, Miyaoka RS, Fisher DR, Gooley TA, Green DJ, Sandmaier BM, Martin PS, Gopal AK.   +10 more
europepmc   +1 more source

Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig.

New England Journal of Medicine, 2003
J. Kremer, R. Westhovens, M. Léon, Eduardo Di Giorgio, R. Alten, S. Steinfeld, A. Russell, M. Dougados, P. Emery, I. Nuamah, G. Williams, J. Becker, D. Hagerty, L. Moreland   +13 more
semanticscholar   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Human opsin restoration by histone methylation using methyltransferase fusion protein SETD7-dCas9. [PDF]

Mol Ther Nucleic Acids
Tran NL, Kang YE, Jeong H, Kim Y, Shin SC, Kim SH, Park B, Oh SJ.   +7 more
europepmc   +1 more source

Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein. The Soluble TNF Receptor Sepsis Study Group.

New England Journal of Medicine, 1996
C. Fisher, J. Agosti, S. Opal, S. Lowry, R. Balk, J. Sadoff, E. Abraham, R. Schein, E. Benjamin   +8 more
semanticscholar   +1 more source