Results 101 to 110 of about 2,428,275 (198)

Detection of p190BCR-ABL AND p210BCR-ABL fusion transcripts in patients with chronic myeloid leukemia (CML) using qualitative RT-PCR

Iatreia, 2014
Introduction: Chronic myelogenous leukemia (CML) is characterized by the presence of the Philadelphia chromosome (Ph), resulting from the balanced reciprocal translocation t(9;22)(q34;q11).
Aya Bonilla, Carlos Alberto , Domingo Torres, José , Muskus, Carlos Enrique, Ramírez Gaviria, Gloria , Cuervo Sierra, Jorge , Sierra Sánchez, Margarita , Cuéllar-Ambrosi, Francisco , Botero Garcés, Jorge Humberto, Gloria Artigas A., Carmen , Muñetón, Carlos Mario , Vásquez Palacio, Gonzalo   +10 more
doaj  

Acute lymphoblastic leukemia with e1a3 BCR/ABL fusion protein. A report of two cases

, 2016
B Acute Lymphoblastic leukemia (B-ALL) with Philadelphia chromosome (Ph') is a neoplasm of lymphoblast committed to the B cell lineage. The clinical presentation of B-ALL Ph'+ is similar to B-ALL, but is more common in adults than in children. The e1a3 rare variant is produced by the fusion of BCR exon 1 to ABL exon 3.
Lopez-Andrade, Bernardo, Gutierrez, Antonio, Garcia, Lucia, Cunill, Vanesa, Duran Pastor, Maria Antonia, Sampol Mayol, Antonia, Bernues, Marta, Iglesias, Julio, Ramos-Asensio, Rafael, Llado, Josep, Sanchez, Maria, Carlos Amat, Juan, Martinez-Serra, Jordi   +12 more
openaire   +1 more source

Flow cytometric detection of BCR-ABL fusion proteins in leukemia patients via an immunobead assay

, 2012
Peer ...
Weerkamp, F., Flores-Montero, Juan, Orfao, Alberto   +2 more
openaire   +1 more source

Detection of BCR-ABL fusion transcripts by Fusion FISH imaging.

, 2014
(A) Representation of the organization of the BCR and ABL genes, with arrows indicating reported break point sites (not drawn to scale). The resulting fusion transcripts always contain exon 1 of BCR and exon 11 of ABL. (B) Gray-scale fluorescence images (
Fatu Badiane Markey (543795), Sanjay Tyagi (8954), Mona Batish (543797), William Ruezinsky (543796)   +3 more
core   +1 more source

Synthetic peptide analogs derived from bcr/abl fusion proteins and the induction of heteroclitic human T-cell responses.

Haematologica, 2006
Chronic myelogenous leukemia (CML) presents a unique opportunity to develop therapeutic strategies using vaccination against a truly tumor-specific antigen that is also the oncogenic protein required for neoplasia. We have shown in phase I and II trials that a tumor-specific, bcr-abl-derived peptide vaccine can be safely administered to patients with ...
Javier, Pinilla-Ibarz, Tatyana, Korontsvit, Victoriya, Zakhaleva, Wendy, Roberts, David A, Scheinberg   +4 more
openaire   +1 more source

The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype [editorial; comment] [PDF]

Blood, 1996
openaire   +1 more source

J Registry Manag [PDF]

IntroductionNational and International Hematology/Oncology Practice Guidelines recommend testing for the BCR-ABL mutation for definitive diagnosis of chronic myeloid leukemia (CML) to allow for appropriate treatment with a Tyrosine Kinase Inhibitor (TKI).

core  

The partner gene modulates response to asciminib in ABL1-rearranged Acute Lymphoblastic Leukemia. [PDF]

Neoplasia
Eadie LN, McDougal DP, Lagonik E, Schutz CE, Page EC, Conlin TS, Rehn J, Bruning JB, Moore AS, Yeung DT, Hughes TP, White DL.   +11 more
europepmc   +1 more source

Successful induction of remission with azacitidine, venetoclax, and dasatinib followed by allogeneic hematopoietic stem cell transplantation in a patient with Philadelphia chromosome-positive mixed phenotype acute leukemia (B/myeloid): a case report. [PDF]

Front Med (Lausanne)
Zhang J, Huang Y, Luo L, Huang K, Pang Y.   +4 more
europepmc   +1 more source

Phosphorylation activity and specificity of the oncogenic tyrosine kinase fusion protein BCR/ABL

Dissertation Karl-Franzens-Universität Graz ...
openaire   +1 more source