Results 151 to 160 of about 19,722 (182)

The BCR-ABL Fusion Protein Sensitizes Acute Lymphoblastic Leukemia to Apoptotic Death Induced by the Dual Glycolytic and Glycosylation Inhibitor 2-Deoxy-D-Glucose.

Blood, 2012
Abstract Abstract 2439 Tumor metabolism has emerged as a hallmark of cancer by which the oncogenic profile of cancer cells pairs energy availability with cell growth and survival. BCR-ABL positive acute lymphoblastic leukemia (BCR-ABL+ ALL) is a highly resistant phenotype, and the BCR-ABL fusion protein has been correlated
Jianfeng Du, Julio C. Barredo, Gilles M. Leclerc, Guy J. Leclerc, Joanna DeSalvo   +4 more
openaire   +2 more sources

[Construction and expression of a vector containing protein transduction domain and bcr/abl fusion gene].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2002
To construct a vector containing protein transduction domain (PTD) and bcr/abl fusion gene of chronic myelogenous leukemia and express PTD-bcr/abl fusion protein in E. Coli.DNA fragment encoding PTD was synthesized and fused to PCR-amplified bcr/abl gene fragment, then inserted into plasmid pET-16b to get the expression vector pEPb containing PTD-bcr ...
Yingmin, Liang, Qiang, Sun, Shanshan, Jiang, Jizhu, Wang, Rongli, Wu, Ping, Chen, Li, Liu, Hua, Han   +7 more
openaire   +1 more source

Deubiquitylase USP25 prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cells

Oncogene, 2020
N. Shibata, Nobumichi Ohoka, Genichiro Tsuji, Yosuke Demizu, Keiji Miyawaza, K. Ui-Tei, T. Akiyama, M. Naito   +7 more
semanticscholar   +1 more source

Detection and significance of bcr-abl mRNA transcripts and fusion proteins in Philadelphia-positive adult acute lymphoblastic leukemia.

Leukemia, 1993
Blast cells from an unselected consecutive series of 84 adults presenting with acute lymphoblastic leukemia (ALL) to St Bartholomew's Hospital over a seven year period were tested prospectively by cytogenetic and retrospectively by RT-PCR analysis for the presence of the Ph translocation and bcr-abl mRNA. This combination gave an overall figure of 20.3%
A, Tuszynski, S, Dhut, B D, Young, T A, Lister, A Z, Rohatiner, J A, Amess, T, Chaplin, E, Dorey, B, Gibbons   +8 more
openaire   +1 more source

Burning plasma achieved in inertial fusion

Nature, 2022
H W Herrmann, V Geppert-kleinrath, J M Koning   +2 more
exaly  

BCR/ABL Fusion Proteins

, 2002
B. Calabretta
semanticscholar   +1 more source

Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion

Nature, 2020
Steven J Gamblin, Antoni G Wrobel, Donald J Benton   +2 more
exaly  

[Signal transduction BCR-ABL fusion protein: analysis of BCR-ABL functional domains].

[Rinsho ketsueki] The Japanese journal of clinical hematology, 1998
T, Tauchi, S, Okabe, K, Oyashiki, K, Sotoyama   +3 more
openaire   +1 more source

Translating cancer genomes and transcriptomes for precision oncology

Ca-A Cancer Journal for Clinicians, 2016
Sameek Roychowdhury, Arul M Chinnaiyan
exaly  

Recent progress in the understanding, diagnosis, and treatment of gastroenteropancreatic neuroendocrine tumors

Ca-A Cancer Journal for Clinicians, 2011
Kiran K Turaga
exaly