Results 91 to 100 of about 675,878 (209)

Rabaptin5 is recruited to endosomes by Rab4a and Rabex5 to regulate endosome maturation [PDF]

open access: yes, 2014
Membrane trafficking between organelles is fundamental to the existence of eukaryotic cells. A multitude of proteins is involved in membrane trafficking, acting as building blocks for transport carriers, regulators of transport, and targeting and fusion ...
Kälin, Simone
core   +1 more source

System for Cleavable Fc Fusion Proteins Using Tobacco Etch Virus (TEV) Protease

open access: yesBioTechniques, 2001
We describe a novel Fc fusion protein system that can be cleaved by tobacco etch virus (TEV) protease. This system is desirable because it takes advantage of the high specificity of TEV protease and its activity at 4°C.
Jeffrey Haspel   +3 more
doaj   +1 more source

ProtFus: A Comprehensive Method Characterizing Protein-Protein Interactions of Fusion Proteins.

open access: yesPLoS Computational Biology, 2019
Tailored therapy aims to cure cancer patients effectively and safely, based on the complex interactions between patients' genomic features, disease pathology and drug metabolism.
Somnath Tagore   +3 more
doaj   +1 more source

Analysis of Nucleolar Protein Dynamics Reveals the Nuclear Degradation of Ribosomal Proteins [PDF]

open access: yes, 2007
Background: The nucleolus is a subnuclear organelle in which rRNAs are transcribed, processed, and assembled with ribosomal proteins into ribosome subunits.
Lamond, Angus I.   +13 more
core   +1 more source

Exploring the function and evolution of proteins using domain families [PDF]

open access: yes, 2009
Proteins are frequently composed of multiple domains which fold independently. These are often evolutionarily distinct units which can be adapted and reused in other proteins.
Reid, A.J., Reid, A J
core  

A PagP fusion protein system for the expression of intrinsically disordered proteins in E. coli

open access: yes, 2012
PagP, a beta-barrel membrane protein found in Gram-negative bacteria, expresses robustly in inclusion bodies when its signal sequence is removed. We have developed a new fusion protein expression system based on PagP and demonstrated its utility in the ...
Pan, Jonathan S.   +2 more
core   +1 more source

The Viral Replication Complex Is Associated with the Virulence of Newcastle Disease Virus

open access: yes, 2010
Virulent strains of Newcastle disease virus ([NDV] also known as avian paramyxovirus type 1) can be discriminated from low-virulence strains by the presence of multiple basic amino acid residues at the proteolytic cleavage site of the fusion (F) protein.
Peeters, B.P.H.   +7 more
core   +1 more source

An acidic region of the 89K murine cytomegalovirus immediate early protein interacts with DNA [PDF]

open access: yes, 1992
The product of the ie 1 gene, the regulatory immediate early protein pp89 of murine cytomegalovirus (MCMV), interacts with core histones, which can mediate the association of pp89 with DNA.
Plachter, Bodo   +3 more
core  

Modification of potato starch granule structure and morphology in planta by expression of starch binding domain fusion proteins

open access: yes, 2010
Producing starches with altered composition, structure and novel physico-chemical properties in planta by manipulating the enzymes which are involved in starch metabolism or (over)expressing heterologous enzymes has huge advantages such as broadening the
Huang, X.
core  

C-terminal fluorescent labeling impairs functionality of DNA mismatch repair proteins

open access: yes, 2012
The human DNA mismatch repair (MMR) process is crucial to maintain the integrity of the genome and requires many different proteins which interact perfectly and coordinated.
Hinrichsen, Inga Malena   +17 more
core   +1 more source

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