Results 71 to 80 of about 675,878 (209)

A mechanism of protein localization : the signal hypothesis and bacteria [PDF]

, 1980
We are studying the molecular mechanism of cellular protein localization. The availability of genetic techniques, such as gene fusion in Escherichia coli, has made this problem particularly amenable to study in this prokaryote.
Hall, M. N., Silhavy, T. J., Emr, S. D., T J Silhavy, S D Emr, M N Hall   +5 more
core   +1 more source

Multimodal Protein Constructs for Herbivore Insect Control

Toxins, 2012
Transgenic plants expressing combinations of microbial or plant pesticidal proteins represent a promising tool for the efficient, durable control of herbivorous insects.
Frank Sainsbury, Meriem Benchabane, Marie-Claire Goulet, Dominique Michaud   +3 more
doaj   +1 more source

Partial Functional Rescue of Helicoverpa armigera Single Nucleocapsid Nucleopolyhedrovirus Infectivity by Replacement of F Protein with GP64 from Autographa californica Multicapsid Nucleopolyhedrovirus

, 2010
Two distinct envelope fusion proteins (EFPs) (GP64 and F) have been identified in members of the Baculoviridae family of viruses. F proteins are found in group II nucleopolyhedroviruses (NPVs) of alphabaculoviruses and in beta- and deltabaculoviruses ...
Feifei Yin, Shu Shen, Just M. Vlak, Fei Deng, Shen, S., Vlak, J.M., Deng, F., Manli Wang, Ying Tan, Yin, F.F., Hu, Z.H., Wang, M.L., Hualin Wang, Zhihong Hu, Tan, Y., Wang, H.L.   +15 more
core   +1 more source

Infant acute leukemia with lineage switch at relapse expressing a novel t(4;11)(q21;q23) MLL-AF4 fusion transcript

Romanian Journal of Laboratory Medicine, 2013
Introducere. Pacienţii cu leucemie acuta limfoblastică (LAL) neonatală prezintă în mod frecvent, o tran- slocaţie particulară, t(4;ll)(q21;q23), care duce la fuziunea genei MLL (mixed lineage leukemia) de pe cromo- zomul 11 cu gena AF4 de pe cromozomul 4.
Ivanov Iuliu C., Jitam Daniela, Grigore Georgiana E., Zlei Mihaela, Ivanov Anca V., Dumitraş Silvia, Carasevici Eugen, Miron Ingritli C.   +7 more
doaj   +1 more source

Emergence of the mitochondrial reticulum from fission and fusion dynamics

, 2012
Mitochondria form a dynamic tubular reticulum within eukaryotic cells. Currently, quantitative understanding of its morphological characteristics is largely absent, despite major progress in deciphering the molecular fission and fusion machineries ...
Michael Meyer-Hermann, Michael Meyer-Hermann (124166), Andreas S. Reichert (124162), Sukhorukov, Valerii M., Daniel Dikov (124160), Valerii M. Sukhorukov (124158), Reichert, Andreas, Valerii M. Sukhorukov, Dikov, Daniel, Andreas S. Reichert, Meyer-Hermann, Michael (Prof. Dr.), Valerii M Sukhorukov, Daniel Dikov, Andreas S Reichert   +13 more
core   +1 more source

Comparison of Immune Responses to Different Versions of VLP Associated Stabilized RSV Pre-Fusion F Protein

Vaccines, 2019
Efforts to develop a vaccine for respiratory syncytial virus (RSV) have primarily focused on the RSV fusion protein. The pre-fusion conformation of this protein induces the most potent neutralizing antibodies and is the focus of recent efforts in vaccine
Lori M. Cullen, Madelyn R. Schmidt, Gretel M. Torres, Adam A. Capoferri, Trudy G. Morrison   +4 more
doaj   +1 more source

The yeast vacuolar membrane proteome [PDF]

, 2009
Transport of solutes between the cytosol and the vacuolar lumen is of crucial importance for various functions of vacuoles, including ion homeostasis; detoxification; storage of different molecules such as amino acids, phosphate, and calcium ions; and ...
Poolman, Bert,, Slotboom, Dirk J.,, Breitling, Rainer, Permentier, Hjalmar P.,, Gandhi, Tejas, Breitling, R., Breitling, Rainer,, Slotboom, D.J., Gandhi, Tejas,, Permentier, Hjalmar P., Permentier, H.P., Gandhi, T., Wiederhold, Elena,, Poolman, Bert, Wiederhold, Elena, Wiederhold, E., Poolman, B., Permentier, Hjalmar P.; id_orcid, Slotboom, Dirk J.   +18 more
core   +1 more source

Coordinated oncogenic transformation and inhibition of host immune responses by the PAX3-FKHR fusion oncoprotein

, 2005
Tumors have evolved elaborate mechanisms for evading immune detection, such as production of immunoinhibitory cytokines and down-regulation of major histocompatibility complex (MHC) expression.
Hubank, M, Antigoni Papanastasiou, Nabarro, S, Sebire, N, Himoudi, N, Papanastasiou, A, Blundell, MP, Gibson, S, Gilmour, K, Anderson, J, Adrian Thrasher, Neil Sebire, John Anderson, Mike Hubank, Nourredine Himoudi, Kimberly Gilmour, Sian Gibson, Canderan, G, Stephen Nabarro, Glenda Canderan, Thrasher, A, Michael P. Blundell   +21 more
core   +1 more source

The Sec1/Munc18 protein Vps45 regulates cellular levels of its SNARE binding partners Tlg2 and Snc2 in Saccharomyces cerevisiae [PDF]

, 2012
Intracellular membrane trafficking pathways must be tightly regulated to ensure proper functioning of all eukaryotic cells. Central to membrane trafficking is the formation of specific SNARE (soluble N-ethylmeleimide-sensitive factor attachment protein ...
Marion S Struthers, Nia J Bryant, Lindsay N Carpp, Carpp Lindsay N., Shanks, S.G., McCann Rebecca K., Carpp, L.N., Struthers, M.S., Bryant, N.J., Scott G Shanks, Struthers Marion S., McCann, R.K., Bryant Nia J., Hong, W., Shanks Scott G., Rebecca K McCann   +15 more
core   +1 more source

Structural Transition and Antibody Binding of EBOV GP and ZIKV E Proteins from Pre-Fusion to Fusion-Initiation State

Biomolecules, 2018
Membrane fusion proteins are responsible for viral entry into host cells—a crucial first step in viral infection. These proteins undergo large conformational changes from pre-fusion to fusion-initiation structures, and, despite differences in viral
Anna Lappala, Wataru Nishima, Jacob Miner, Paul Fenimore, Will Fischer, Peter Hraber, Ming Zhang, Benjamin McMahon, Chang-Shung Tung   +8 more
doaj   +1 more source