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Fusobacterium nucleatum and colorectal cancer: A mechanistic overview
Journal of Cellular Physiology, 2019 Colorectal cancer (CRC) is the third most prevalent cancer in the world. There are many risk factors involved in CRC. According to recent findings, the tumor microenvironment and feces samples of patients with CRC are enriched by Fusobacterium nucleatum.
Babak Negahdari +2 more
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Characterization of Proteolytic Activities of Fusobacterium nucleatum
Journal of Endodontics, 2006This investigation attempted to detect the proteolytic activity of Fusobacterium nucleatum in living cells, lysate cells, and supernatant of cultures. The reactions were optimized in their pH, temperature, reaction time, enzyme source, and substrate volume.
Alice Tayoko, Ogawa +4 more
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Pathway of lysine degradation in Fusobacterium nucleatum
Journal of Bacteriology, 1982Lysine was fermented by Fusobacterium nucleatum ATCC 25586 with the formation of about 1 mol each of acetate and butyrate. By the use of [1-14C]lysine or [6-14C]lysine, acetate and butyrate were shown to be derived from both ends of lysine, with acetate being formed preferentially from carbon atoms 1 and 2 and butyrate being formed preferentially from ...
H A, Barker, J M, Kahn, L, Hedrick
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Neutrophil chemiluminescence in response to Fusobacterium nucleatum
Journal of Periodontal Research, 1982During the interaction of bacteria or other particles with neutrophils, oxygen consumption is increased, and unstable reduction products are produced. Chemiluminescence is the light energy produced in the neutrophil by the generation of unstable oxygen radicals. These oxygen radicals are thought to be important in the destruction of bacteria as well as
S A, Passo, S A, Syed, J, Silva
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Fusobacterium nucleatum Endocarditis Mimicking Polymyalgia Rheumatica
Southern Medical Journal, 2009A case of Fusobacterium nucleatum endocarditis in an 80-year-old man is reported. The patient presented with a headache and nonspecific musculoskeletal symptoms and was misdiagnosed as having polymyalgia rheumatica. The diagnosis of bacterial endocarditis was delayed because of an insidious presentation, typical in infections with low virulence micro ...
De Socio G. +3 more
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Fusobacterium nucleatum in endodontic flare-ups
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 2002The extent to which Fusobacterium nucleatum is recovered from root canals of teeth that present with an interappointment flare-up following endodontic instrumentation was investigated.Included in the study were 28 patients that sought emergency treatment after initiation of root canal therapy.
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The heat shock response of Fusobacterium nucleatum
European Journal of Oral Sciences, 2001The heat‐shock response of the oral Gram‐negative bacterium Fusobacterium nucleatum was examined. Different strains of F. nucleatum were grown at 37°C, 42°C and 48°C in the presence of [35S]methionine. Cellular proteins synthesised after shifts to higher temperatures were analysed by SDS‐PAGE and autoradiography.
C K, Skar, V, Bakken
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Fusobacterium nucleatum: ecology, pathogenesis and clinical implications
Nature Reviews MicrobiologyFusobacterium nucleatum, a commensal microorganism and opportunistic pathogen (a pathobiont), has emerged as a key player in both local and systemic diseases. In humans, F. nucleatum is found in the oral microbiota, but under certain conditions, it can spread to other ecological niches within the body, such as the gut microbiota.
Shan-Shan Jiang +2 more
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