Results 81 to 90 of about 4,088 (175)

Representative images of immunohistochemistry for FUT8 and p53 expression in colorectal cancer.

, 2018
(A) FUT8 protein expression in colon carcinoma [T] and adjacent colon mucosa [N]. (B) FUT8 was not expressed by non-neoplastic colon mucosal cells. (C) FUT8 staining was typically found in cytoplasm of tumor cells.
Hirokazu Okayama (727077), Tomoyuki Momma (5485286), Masaru Noda (1595053), Shotaro Fujita (5485268), Motonobu Saito (237122), Shinji Ohki (5485292), Wataru Sakamoto (214289), Keita Aoto (5485271), Hisahito Endo (5485280), Shun Chida (5485289), Takeshi Tada (5485277), Takahiro Nakajima (61561), Mai Ashizawa (5485274), Katsuharu Saito (197101), Koji Kono (142779), Yasuhide Kofunato (5485295), Tomohiro Kikuchi (5485283)   +16 more
core   +1 more source

Sequential, chromosome‐specific glutamine synthetase double knockout with Cas‐CLOVER establishes enhanced CHO platforms for cell line development

Biotechnology Progress, Volume 42, Issue 2, March/April 2026.
This study established the first creation of a commercially available double GS knockout (DKO) from a single KO in CHO‐K1 cells, called CleanCut GS CHO using Cas‐CLOVER. When combined with the Harbor‐IN transposase system, CleanCut GS CHO cells demonstrated a highly antibody productivity.
Cintia Gomez Limia, Valeriya Steffey, Hsueh Che Cheng, Daniel Machado, Thomas Hart, Mark Cameron McHargue, Corey Brizzee, Jack Crawford   +7 more
wiley   +1 more source

Construction of a Multitissue Cell Atlas Reveals Cell‐Type‐Specific Regulation of Molecular and Complex Phenotypes in Pigs

Advanced Science, Volume 13, Issue 8, 9 February 2026.
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen, Houcheng Li, Jinyan Teng, Zhen Wang, Xiaolu Qu, Zhe Chen, Xiaodian Cai, Haonan Zeng, Zhonghao Bai, Jinghui Li, Xiangchun Pan, Leyan Yan, Fei Wang, Lin Lin, Yonglun Luo, Goutam Sahana, Mogens Sandø Lund, Maria Ballester, Daniel Crespo‐Piazuelo, Peter Karlskov‐Mortensen, Merete Fredholm, Alex Clop, Marcel Amills, Crystal Loving, Christopher K. Tuggle, Ole Madsen, Jiaqi Li, Zhe Zhang, George E. Liu, Jicai Jiang, Lingzhao Fang, Guoqiang Yi   +31 more
wiley   +1 more source

FGF2 Induces Migration of Human Bone Marrow Stromal Cells by Increasing Core Fucosylations on N-Glycans of Integrins

Stem Cell Reports, 2018
Summary: Since hundreds of clinical trials are investigating the use of multipotent stromal cells (MSCs) for therapeutic purposes, effective delivery of the cells to target tissues is critical.
Baarkullah Awan, David Turkov, Cameron Schumacher, Antonio Jacobo, Amber McEnerney, Ashley Ramsey, Gege Xu, Dayoung Park, Stefanos Kalomoiris, Wei Yao, Li-En Jao, Miguel L. Allende, Carlito B. Lebrilla, Fernando A. Fierro   +13 more
doaj   +1 more source

p53 and FUT8 regulate the introduction of Fuc-Lip-Cy5.5 into HCC cells.

, 2016
(A) Expression levels of p53 and FUT8 in HCC cells were examined by western blot. (B) Quantification of AFP-L3 values. (C) Determination of the introduction of Fuc-Lip-Cy5.5 into HCC cells. After siRNA transfection, HepG2 and JHH7 cells were exposed to 1
Hajime Nakamura (3428984), Yusuke Kamihara (3214998), Naotaka Hayasaka (3560810), Makoto Usami (757009), Koji Miyanishi (151762), Kazuyuki Murase (151747), Yutaka Okagawa (3560807), Junji Kato (151778), Takahiro Osuga (151758), Masayoshi Kobune (151774), Kohichi Takada (151767), Shohei Kikuchi (832677), Yohei Arihara (3560813)   +12 more
core   +1 more source

Receiver operating characteristic curve for evaluating epilepsy and refractory epilepsy by Fut8.

, 2023
A. Fut8 could distinguish the epilepsy patients from healthy controls with an AUC of 0.620. B. Fut8 could distinguish the refractory epilepsy patients from healthy controls with an AUC of 0.856.
Zhou Zhang (197948), Yunxiu Huang (15285530), Linmu Chen (14439559)   +2 more
core   +1 more source

Molecular cloning, characterization, genomic organization and promoter analysis of the α1,6-fucosyltransferase gene (fut8) expressed in the rat hybridoma cell line YB2/0

BMC Biotechnology, 2011
Background The rat hybridoma cell line YB2/0 appears a good candidate for the large-scale production of low fucose recombinant mAbs due to its lower expression of fut8 gene than other commonly used rodent cell lines.
Harduin-Lepers Anne, Bobowski Marie, Meurice Edwige, Teylaert Béatrice, Gaucher Christine, Fontayne Alexandre, Jorieux Sylvie, Delannoy Philippe   +7 more
doaj   +1 more source

Articular cartilage corefucosylation regulates tissue resilience in osteoarthritis

eLife
This study aimed to investigate the glycan structural changes that occur before histological degeneration in osteoarthritis (OA) and to determine the mechanism by which these glycan conformational changes affect cartilage degeneration.
Kentaro Homan, Tomohiro Onodera, Hisatoshi Hanamatsu, Jun-ichi Furukawa, Daisuke Momma, Masatake Matsuoka, Norimasa Iwasaki   +6 more
doaj   +1 more source

Core fucosylation regulates the ovarian response via FSH receptor during follicular development

Journal of Advanced Research
Introduction: Ovarian low response to follicle-stimulating hormone (FSH) causes infertility featuring hypergonadotropic hypogonadism, ovarian failure, and/or defective ovarian response.
Tiantong Wang, Zhiwei Zhang, Changduo Qu, Wanli Song, Ming Li, Xiaoguang Shao, Tomohiko Fukuda, Jianguo Gu, Naoyuki Taniguchi, Wenzhe Li   +9 more
doaj   +1 more source

Clinicopathologic significance of FUT8, STX4, and calpain2 expression in ovarian cancer

American Journal of Translational Research
To investigate the expression of FUT8, STX4, and calpain2 in ovarian tumor tissues and their association with clinicopathological characteristics.This retrospective study analyzed the expression of FUT8, STX4, and calpain2 in ovarian tumor samples from patients treated at Shanghai Pudong New Area People's Hospital between January 1, 2008, and December ...
Yumei, Yang, Mei, Wang, Linlin, Chen, Xiangnan, Chen, Yuhua, Wang, Wenfeng, Ye   +5 more
openaire   +2 more sources