Results 131 to 140 of about 5,464,381 (308)

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Academic performance as a driver for the development of reasoning for complexity and digital transformation competencies

Frontiers in Education
This study analyzed the relationship between academic performance and the development of transversal competencies of reasoning for complexity and digital transformation in higher education students.
José Martín Molina-Espinosa, Paloma Suárez-Brito, Benjamín Gutiérrez-Padilla, Edgar Omar López-Caudana, Miguel González-Mendoza   +4 more
doaj   +1 more source

Books or Baskets: Compromising the Education and Future of Black Student-Athletes [PDF]

, 2018
In this paper, I discuss the challenges and inequalities that Black male athletes face while playing college sports, particularly basketball and football at PWIs.
Laemle, Jessica L.
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Entrepreneurship education and self-efficacy among Chinese college students mediated by harmonious passion and moderated by parental psychological control

Scientific Reports
Despite the rapid development of entrepreneurship education among college students, limited research has examined the hindering role of Chinese parents in this process under the socio-cultural context of China.
Yuan Gao, Jinjin Lu
doaj   +1 more source

Analyzing Future Skills Adoption by Top-100 Universities of QS-Ranking: Present and Future Skills Opportunities

IEEE Access
The purpose of this study was to examine how, in recent years, the top 100 universities in the QS ranking have integrated the development of Future Skills into their curricula to address the evolving demands of the labor market.
Luis Alberto Mejia-Manzano, Jose Daniel Azofeifa, Valentina Rueda-Castro, Nicolas Otaduy-Rivera, Patricia Caratozzolo   +4 more
doaj   +1 more source

The Future of Education Reform: The Role of Emotional Intelligence for School Leaders [PDF]

, 2014
With the demands for better outcomes and greater change from school leaders such as superintendents, principals, central and building-level administrators, there is a need to understand how emotional intelligence can help these leaders meet new demands ...
Cianca, Marie, Cleverley-Thompson, Shannon   +1 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

THE FUTURE OF EXTENSION PUBLIC POLICY EDUCATION [PDF]

Public Economics,
Hildreth, R.J.
core   +1 more source

Library purchasing consortia in the UK: activity and practice [PDF]

, 1999
This Briefing is based on a survey undertaken for a BLRIC/LIC-funded research project (RIC/G/403). It describes the models of operation of purchasing consortia in four library sectors (further education, health, higher education and public libraries ...
Ball, David, Pye, Jo
core