Cancer Treatment and Research Communications, 2021 Background: The clinical utility of prophylactic granulocyte-colony stimulating factor (G-CSF) in patients receiving platinum agents plus etoposide for neuroendocrine carcinoma (NEC) is unknown.
Hirofumi Watanabe +11 more
doaj +1 more source
Predictive value of hematological and phenotypical parameters on postchemotherapy leukocyte recovery [PDF]
, 2009 Background: Grade IV chemotherapy toxicity is defined as absolute neutrophil count <500/μL. The nadir is considered as the lowest neutrophil number following chemotherapy, and generally is not expected before the 7th day from the start of chemotherapy.
Abbasciano V +15 more
core +1 more source
The effects of hematopoietic growth factors on neurite outgrowth. [PDF]
PLoS ONE, 2013 Stem cell factor (SCF) and granulocyte colony-stimulating factor (G-CSF) are initially discovered as the essential hematopoietic growth factors regulating bone marrow stem cell proliferation and differentiation, and SCF in combination with G-CSF (SCF+G ...
Ye Su +4 more
doaj +1 more source
G-CSF or not G-CSF? That is the question [PDF]
Bone Marrow Transplantation, 2004 Although administration of myeloid colony-stimulating factors (G-CSF or GM-CSF) has been routinely used to increase the rate of neutrophil recovery, evidence suggests that clinical efficacy in the transplant setting is doubtful (Table 1). We performed two consecutive prospective randomized trials to assess the use of G-CSF (filgrastim) after autologous
M A Canales, F Hernández-Navarro
openaire +1 more source
The use of chemotherapy regimens carrying a moderate or high risk of febrile neutropenia and the corresponding management of febrile neutropenia: an expert survey in breast cancer and non-Hodgkin's lymphoma [PDF]
, 2010 Background: The use of chemotherapy regimens with moderate or high risk of febrile neutropenia (defined as having a FN incidence of 10% or more) and the respective incidence and clinical management of FN in breast cancer and NHL has not been studied in ...
Gerlier, Laetitia +13 more
core +2 more sources
Immune Evasion of G-CSF and GM-CSF in Lung Cancer [PDF]
Tuberculosis and Respiratory DiseasesTumor immune evasion is a complex process that involves various mechanisms, such as antigen recognition restriction, immune system suppression, and T cell exhaustion.
Yeonhee Park, Chaeuk Chung
doaj +1 more source
The granulocyte colony stimulating factor pathway regulates autoantibody production in a murine induced model of systemic lupus erythematosus [PDF]
, 2013 INTRODUCTION: An NZB-derived genetic locus (Sle2c2) that suppresses autoantibody production in a mouse model of induced systemic lupus erythematosus contains a polymorphism in the gene encoding the G-CSF receptor.
Clive Wasserfall +6 more
core +1 more source
Journal of Research in Medical Sciences, 2018 Background: Myelosuppression is one of the frequent side effects of chemotherapy in breast cancer patients. Granulocyte-colony stimulating factor (G-CSF) and pegylated G-CSF are used for the prevention of neutropenia after chemotherapy.
Farzaneh Ashrafi, Mehrzad Salmasi
doaj +1 more source
Effect in supralethally irradiated rats of granulocyte colony- stimulating factor and lisofylline on hematopoietic reconstitution by syngeneic bone marrow or whole organ passenger leukocytes [PDF]
, 1997 We have previously shown the existence of migratory hematopoietic stem cells in adult solid organs. This study demonstrates that granulocyte colony- stimulating factor (G-CSF) and lisofylline, a phosphatidic acid inhibitor that suppresses hematopoiesis ...
Abdul Rao +23 more
core +1 more source
Macrophage depletion disrupts immune balance and energy homeostasis. [PDF]
, 2014 Increased macrophage infiltration in tissues including white adipose tissue and skeletal muscle has been recognized as a pro-inflammatory factor that impairs insulin sensitivity in obesity.
Feng, Gen-Sheng +4 more
core +6 more sources