Results 21 to 30 of about 12,166,273 (260)

The effects of hematopoietic growth factors on neurite outgrowth. [PDF]

PLoS ONE, 2013
Stem cell factor (SCF) and granulocyte colony-stimulating factor (G-CSF) are initially discovered as the essential hematopoietic growth factors regulating bone marrow stem cell proliferation and differentiation, and SCF in combination with G-CSF (SCF+G ...
Ye Su, Lili Cui, Chunshu Piao, Bin Li, Li-Ru Zhao   +4 more
doaj   +1 more source

Comparative Histological and Immunohistochemical Study of the Potential Protective Effects of Granulocyte Colony Stimulating Factor Versus Galangin on Induced Cardiac Toxicity in Adult Male Albino Rats [PDF]

The Egyptian Journal of Histology
Introduction: Cardiomyopathy, which is distinguished by biochemical and histological alterations, significantly contributes to worldwide mortality, particularly ventricular infarction.Objective: Is to assess histological alterations within the myocardium
Hala El-Haroun, nadia badawy khair, eman konsowa, mona soliman   +3 more
doaj   +1 more source

G-CSF for Extensive STEMI [PDF]

, 2019
Rationale: In the exploratory Phase II STEM-AMI (Stem Cells Mobilization in Acute Myocardial Infarction) trial, we reported that early administration of G-CSF (granulocyte colony-stimulating factor), in patients with anterior ST-segment-elevation ...
Bassetti B., Mircoli L., Colombo G. I., Righetti S., Guglielmo M., Ceseri M., Di Gennaro F., Facchini C., Lenatti L., Di Tano G., Pompilio G., Scarpa D., Squadroni L., Maggiolini S., Esposito Giovanni, Pidello S., Soffici F., Malafronte C., Esposito G., Achilli F., Corrada E., Baggiano A., Muscogiuri G., Pontone G., Campodonico J., Limido A.   +25 more
core   +1 more source

Prophylactic granulocyte-colony stimulating factor in patients with lung neuroendocrine carcinoma receiving platinum agents plus etoposide

Cancer Treatment and Research Communications, 2021
Background: The clinical utility of prophylactic granulocyte-colony stimulating factor (G-CSF) in patients receiving platinum agents plus etoposide for neuroendocrine carcinoma (NEC) is unknown.
Hirofumi Watanabe, Masato Karayama, Hideki Yasui, Yusuke Inoue, Hironao Hozumi, Yuzo Suzuki, Kazuki Furuhashi, Tomoyuki Fujisawa, Noriyuki Enomoto, Yutaro Nakamura, Naoki Inui, Takafumi Suda   +11 more
doaj   +1 more source

Eradication of chronic myeloid leukemia stem cells: a novel mathematical model predicts no therapeutic benefit of adding G-CSF to imatinib [PDF]

, 2009
Imatinib mesylate induces complete cytogenetic responses in patients with chronic myeloid leukemia (CML), yet many patients have detectable BCR-ABL transcripts in peripheral blood even after prolonged therapy.
Holyoake, T., Tessa Holyoake, Michor Franziska, Michor, F., Holyoake Tessa, Clarkson Bayard, Foo, J., Mark W Drummond, Franziska Michor, Bayard Clarkson, Foo Jasmine, Drummond, M.W., Jasmine Foo, Clarkson, B., Drummond Mark W.   +14 more
core   +2 more sources

G-CSF protects motoneurons against axotomy-induced apoptotic death in neonatal mice

BMC Neuroscience, 2010
Background Granulocyte colony stimulating factor (G-CSF) is a growth factor essential for generation of neutrophilic granulocytes. Apart from this hematopoietic function, we have recently uncovered potent neuroprotective and regenerative properties of G ...
Pitzer Claudia, Henriques Alexandre, Dupuis Luc, Schneider Armin   +3 more
doaj   +1 more source

Glutamine Deprivation Promotes the Generation and Mobilization of MDSCs by Enhancing Expression of G-CSF and GM-CSF

Frontiers in Immunology, 2021
Solid tumors are often challenged by hypoxic and nutrient-deprived tumor microenvironments (TME) as tumors progress, due to limited perfusion and rapid nutrient consumption.
Hong-Wei Sun, Hong-Wei Sun, Wen-Chao Wu, Hai-Tian Chen, Yi-Tuo Xu, Yi-Tuo Xu, Yan-Yan Yang, Yan-Yan Yang, Jing Chen, Xing-Juan Yu, Zilian Wang, Ze-Yu Shuang, Ze-Yu Shuang, Limin Zheng, Limin Zheng   +14 more
doaj   +1 more source

SB203580 increases G-CSF production via a stem-loop destabilizing element in the 3 ' untranslated region in macrophages independently of its effect on p38 MAPK activity

, 2017
Background: Granulocyte-colony stimulating factor (G-CSF) is a major regulator of the production and survival of neutrophils. Regulation of G-CSF expression is complex and occurs at both transcription and post-transcription levels.
Chang, Shwu-Fen;Li, Huai-Ci;Huang, Yu-Pei;Tasi, Wen-Ju;Chou, Yuan-Yi;Lu, Shao-Chun, 呂紹俊   +1 more
core   +1 more source

On-demand plerixafor added to high-dose cyclophosphamide and pegylated recombinant human granulocyte colony-stimulating factor in the mobilization of patients with multiple myeloma: a treatment with high effectiveness, convenient, and affordable cost

Frontiers in Oncology
ObjectiveThe combination of high-dose cyclophosphamide (HD-Cy) (3g/m2) plus granulocyte colony-stimulating factor (G-CSF) and on-demand plerixafor (PXF) has been considered an effective mobilization regimen of patients with multiple myeloma(MM). However,
Li-qiong Hou, Jun-Ru Liu, Jing-Li Gu, Mei-Lan Chen, Li-Fen Kuang, Bei-Hui Huang, Wai-yi Zou, Juan Li   +7 more
doaj   +1 more source

Anti-obesity effects of granulocyte-colony stimulating factor in Otsuka-Long-Evans-Tokushima fatty rats. [PDF]

PLoS ONE, 2014
Granulocyte-colony stimulating factor (G-CSF) has molecular structures and intracellular signaling pathways that are similar to those of leptin and ciliary neurotropic factor (CNTF). It also has immune-modulatory properties.
Yonggu Lee, Yi-Sun Song, Cheng-Hu Fang, Byung-Im So, Jun-Young Park, Hyun-Woo Joo, In-Hwa Park, Guang-Yin Shen, Jeong-Hun Shin, Hyuck Kim, You-Heon Ahn, Kyung-Soo Kim   +11 more
doaj   +1 more source