Results 21 to 30 of about 269,290 (261)
Cancer Treatment and Research Communications, 2021 Background: The clinical utility of prophylactic granulocyte-colony stimulating factor (G-CSF) in patients receiving platinum agents plus etoposide for neuroendocrine carcinoma (NEC) is unknown.
Hirofumi Watanabe +11 more
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Journal of Research in Medical Sciences, 2018 Background: Myelosuppression is one of the frequent side effects of chemotherapy in breast cancer patients. Granulocyte-colony stimulating factor (G-CSF) and pegylated G-CSF are used for the prevention of neutropenia after chemotherapy.
Farzaneh Ashrafi, Mehrzad Salmasi
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Comparative Histological and Immunohistochemical Study of the Potential Protective Effects of Granulocyte Colony Stimulating Factor Versus Galangin on Induced Cardiac Toxicity in Adult Male Albino Rats [PDF]
The Egyptian Journal of HistologyIntroduction: Cardiomyopathy, which is distinguished by biochemical and histological alterations, significantly contributes to worldwide mortality, particularly ventricular infarction.Objective: Is to assess histological alterations within the myocardium
Hala El-Haroun +3 more
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Frontiers in Immunology, 2021 Solid tumors are often challenged by hypoxic and nutrient-deprived tumor microenvironments (TME) as tumors progress, due to limited perfusion and rapid nutrient consumption.
Hong-Wei Sun +14 more
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G-CSF protects motoneurons against axotomy-induced apoptotic death in neonatal mice
BMC Neuroscience, 2010 Background Granulocyte colony stimulating factor (G-CSF) is a growth factor essential for generation of neutrophilic granulocytes. Apart from this hematopoietic function, we have recently uncovered potent neuroprotective and regenerative properties of G ...
Pitzer Claudia +3 more
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Anti-obesity effects of granulocyte-colony stimulating factor in Otsuka-Long-Evans-Tokushima fatty rats. [PDF]
PLoS ONE, 2014 Granulocyte-colony stimulating factor (G-CSF) has molecular structures and intracellular signaling pathways that are similar to those of leptin and ciliary neurotropic factor (CNTF). It also has immune-modulatory properties.
Yonggu Lee +11 more
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Frontiers in Immunology, 2020 Cytokines are known to shape the tumor microenvironment and although progress has been made in understanding their role in carcinogenesis, much remains to learn regarding their role in tumor growth and progression.
Ioannis Karagiannidis +7 more
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Differential regulation of microglial states by colony stimulating factors
Frontiers in Cellular Neuroscience, 2023 Recent studies have emphasized the role of microglia in the progression of many neurodegenerative diseases. The colony stimulating factors, CSF-1 (M-CSF), granulocyte-macrophage CSF (GM-CSF) and granulocyte CSF (G-CSF) regulate microglia through ...
E. Richard Stanley +3 more
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The kinetics of G‐CSF folding [PDF]
Protein Science, 2002 AbstractThe folding kinetics of G‐CSF were determined by trp‐fluorescence and far‐UV circular dichroism. Folding and unfolding was achieved by rapid dilution and mixing of the denaturant, GdnHCl. G‐CSF is a four‐helical bundle protein with two long loops between the first and second helices and between the third and fourth helices.
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Pathophysiological Roles of G-CSF
Journal of Nutritional Science and Vitaminology, 1992 G-CSF is produced by a variety of cells. In situ hybridization showed that only a small proportion of stromal cells expressed G-CSF after stimulation with LPS or IL-1. The measurement of serum G-CSF level by enzyme immunoassay provided valuable information as to the pathophysiological roles of G-CSF. In aplastic anemia, there was an inverse correlation
OZAWA, K. +11 more
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