Disruption of embryonic blood-CSF barrier in chick embryos reveals the actual importance of this barrier to control E-CSF composition and homeostasis in early brain development [PDF]
, 2013 In vertebrates, early brain development takes place at the expanded anterior end of the neural tube. After closure of the anterior neuropore, the brain wall forms a physiologically sealed cavity that encloses embryonic cerebrospinal fluid (E-CSF), a ...
Bueno i Torrens, David, 1965- +1 more
core +6 more sources
Blood stem cell collections after mobilization with combination chemotherapy containing ifosfamide followed by G-CSF in multiple myeloma [PDF]
, 2003 High-dose chemotherapy with autologous peripheral blood stem cell transplantation is the standard treatment of patients with multiple myeloma today. In this study we used a combination mobilizing chemotherapy containing ifosfamide with G-CSF before stem ...
Werding, N. +5 more
core +2 more sources
G-CSF Prevents the Progression of Structural Disintegration of White Matter Tracts in Amyotrophic Lateral Sclerosis: A Pilot Trial [PDF]
, 2011 Background: The hematopoietic protein Granulocyte-colony stimulating factor (G-CSF) has neuroprotective and regenerative properties. The G-CSF receptor is expressed by motoneurons, and G-CSF protects cultured motoneuronal cells from apoptosis.
Tobias Warnecke +32 more
core +1 more source
Stem Cell Mobilization with G-CSF versus Cyclophosphamide plus G-CSF in Mexican Children
Stem Cells International, 2016 Fifty-six aphaereses were performed in 23 pediatric patients with malignant hematological and solid tumors, following three different protocols for PBPC mobilization and distributed as follows: A: seventeen mobilized with 4 g/m2 of cyclophosphamide (CFA)
José Eugenio Vázquez Meraz +4 more
doaj +1 more source
Stem Cell Research & Therapy, 2021 Background Mobilization failure may occur when the conventional hematopoietic stem cells (HSCs) mobilization agent granulocyte colony-stimulating factor (G-CSF) is used alone, new regimens were developed to improve mobilization efficacy. Multiple studies
Chengxin Luo +15 more
doaj +1 more source
Immune Evasion of G-CSF and GM-CSF in Lung Cancer [PDF]
Tuberculosis and Respiratory DiseasesTumor immune evasion is a complex process that involves various mechanisms, such as antigen recognition restriction, immune system suppression, and T cell exhaustion.
Yeonhee Park, Chaeuk Chung
doaj +1 more source
Neutrophil recovery with or without G-CSF in non M3 AML patient with DA 3+7 protocol
Haematology Journal of Bangladesh, 2021 Background: Induction of acute myeloid leukaemia is associated with a high incidence of treatment related mortality mostly due to neutropenia related infections.
Gazi Yeasinul Islam +7 more
doaj +1 more source
Journal of Research in Medical Sciences, 2018 Background: Myelosuppression is one of the frequent side effects of chemotherapy in breast cancer patients. Granulocyte-colony stimulating factor (G-CSF) and pegylated G-CSF are used for the prevention of neutropenia after chemotherapy.
Farzaneh Ashrafi, Mehrzad Salmasi
doaj +1 more source
LPS-Induced G-CSF Expression in Macrophages Is Mediated by ERK2, but Not ERK1. [PDF]
PLoS ONE, 2015 Granulocyte colony-stimulating factor (G-CSF) selectively stimulates proliferation and differentiation of neutrophil progenitors which play important roles in host defense against infectious agents.
Shwu-Fen Chang +5 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Myeloid-derived suppressor cells (MDSCs) are major immunosuppressive cells that accumulate in tumor-bearing hosts. Since MDSCs suppress anti-tumor immunity and promote tumor progression, they are promising targets for cancer immunotherapy.
Zhiqi Xie +7 more
doaj +1 more source