Results 11 to 20 of about 269,290 (261)

G-CSF, the guardian of granulopoiesis

Seminars in Immunology, 2021
A considerable amount of continuous proliferation and differentiation is required to produce daily a billion new neutrophils in an adult human. Of the few cytokines and factors known to control neutrophil production, G-CSF is the guardian of granulopoiesis.
Hrishikesh M. Mehta, Seth J. Corey
openaire   +2 more sources

Uso do estimulante de colônia de granulócitos nas neutropenias em cães e gatos Granulocyte colony-stimulating factor use in neutropenias in dogs and cats

Ciência Rural, 2007
As neutropenias persistentes podem ser decorrentes de alterações na granulopoiese, causadas por efeitos supressivos ou tóxicos à medula óssea, predispõem o paciente a infecções comprometendo sua sobrevida.
Cynthia de Assumpção Lucidi, Regina Kiomi Takahira   +1 more
doaj   +1 more source

Development and content validation of the Satisfaction and Experience Questionnaire for Granulocyte Colony-Stimulating Factor (SEQ-G-CSF)

Journal of Patient-Reported Outcomes, 2021
Background Several options for granulocyte colony-stimulating factor (G-CSF) prophylaxis of chemotherapy-induced febrile neutropenia are available to patients worldwide.
Aylin Yucel, Anne Skalicky, Olabimpe Ruth Eseyin, Emre Yucel, Rajesh Belani, Mark Bensink   +5 more
doaj   +1 more source

Application of G-CSF in high-leukocyte acute myeloid leukemia is a poor prognostic factor

Hematology, 2023
Objective To analyze the effect of granulocyte colony-stimulating factor (G-CSF) on outcomes in patients with acute myeloid leukemia (AML).Methods A total of 526 patients with AML in the Haematology Department were enrolled.
Ping Weng, Shu Yang, Shujuan Xu, Shuxia Zhang, Yong Wu, Yuanzhong Chen   +5 more
doaj   +1 more source

Comparison of the efficacy of hematopoietic stem cell mobilization regimens: a systematic review and network meta-analysis of preclinical studies

Stem Cell Research & Therapy, 2021
Background Mobilization failure may occur when the conventional hematopoietic stem cells (HSCs) mobilization agent granulocyte colony-stimulating factor (G-CSF) is used alone, new regimens were developed to improve mobilization efficacy. Multiple studies
Chengxin Luo, Li Wang, Guixian Wu, Xiangtao Huang, Yali Zhang, Yanni Ma, Mingling Xie, Yanni Sun, Yarui Huang, Zhen Huang, Qiuyue Song, Hui Li, Yu Hou, Xi Li, Shuangnian Xu, Jieping Chen   +15 more
doaj   +1 more source

Neutrophil recovery with or without G-CSF in non M3 AML patient with DA 3+7 protocol

Haematology Journal of Bangladesh, 2021
Background: Induction of acute myeloid leukaemia is associated with a high incidence of treatment related mortality mostly due to neutropenia related infections.
Gazi Yeasinul Islam, Mohiuddin Ahmed Khan, Mafruha Akter, H N Ashiqur Rahman, Md. Ibrahim, Md. Adnan Hasan Masud, Md. Nurul Farhad, A S M Tariqur Rabby   +7 more
doaj   +1 more source

LPS-Induced G-CSF Expression in Macrophages Is Mediated by ERK2, but Not ERK1. [PDF]

PLoS ONE, 2015
Granulocyte colony-stimulating factor (G-CSF) selectively stimulates proliferation and differentiation of neutrophil progenitors which play important roles in host defense against infectious agents.
Shwu-Fen Chang, Shih-Shan Lin, Hui-Ching Yang, Yuan-Yi Chou, Jhen-I Gao, Shao-Chun Lu   +5 more
doaj   +1 more source

Targeting GGT1 Eliminates the Tumor-Promoting Effect and Enhanced Immunosuppressive Function of Myeloid-Derived Suppressor Cells Caused by G-CSF

Frontiers in Pharmacology, 2022
Myeloid-derived suppressor cells (MDSCs) are major immunosuppressive cells that accumulate in tumor-bearing hosts. Since MDSCs suppress anti-tumor immunity and promote tumor progression, they are promising targets for cancer immunotherapy.
Zhiqi Xie, Takahiro Kawasaki, Haoyang Zhou, Daisuke Okuzaki, Daisuke Okuzaki, Naoki Okada, Masashi Tachibana, Masashi Tachibana   +7 more
doaj   +1 more source

Immune Evasion of G-CSF and GM-CSF in Lung Cancer [PDF]

Tuberculosis and Respiratory Diseases
Tumor immune evasion is a complex process that involves various mechanisms, such as antigen recognition restriction, immune system suppression, and T cell exhaustion.
Yeonhee Park, Chaeuk Chung
doaj   +1 more source

The effects of hematopoietic growth factors on neurite outgrowth. [PDF]

PLoS ONE, 2013
Stem cell factor (SCF) and granulocyte colony-stimulating factor (G-CSF) are initially discovered as the essential hematopoietic growth factors regulating bone marrow stem cell proliferation and differentiation, and SCF in combination with G-CSF (SCF+G ...
Ye Su, Lili Cui, Chunshu Piao, Bin Li, Li-Ru Zhao   +4 more
doaj   +1 more source