Agonist and antagonist TRUPATH assays for G protein-coupled receptors
Summary: TRUPATH is a bioluminescence resonance energy transfer-based platform for quantifying G protein-coupled receptor activity via dissociation of heterotrimeric G protein biosensors.
Jeffrey F. DiBerto+3 more
doaj
GAP-43 augments G protein-coupled receptor transduction in Xenopus laevis oocytes. [PDF]
Stephen M. Strittmatter+4 more
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Mutation of a highly conserved acidic residue present in the second intracellular loop of G-protein-coupled receptors does not impair hormone binding or signal transduction of the luteinizing hormone/chorionic gonadotropin receptor. [PDF]
Z Wang, H Wang, Mario Ascoli
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Whole body deletion of Gpr68 does not change hematopoietic stem cell function
G protein-coupled receptor 68 (GPR68) responds to extracellular protons, thus called the proton-sensing G protein-coupled receptor (GPCR), leading to activation of the phospholipase C-β (PLCβ)/calcium (Ca2+) pathway or the adenylyl cyclase (AC)/cyclic ...
Xiaofei He+7 more
doaj
Schizophrenia: Normal Sequence in the Dopamine D2 Receptor Region that Couples to G-Proteins. DNA Polymorphisms in D2 [PDF]
Philip Seeman+6 more
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Role of G-protein βγ subunits in the augmentation of P2Y2 (P2U) receptor-stimulated responses by neuropeptide Y Y1 Gi/o-coupled receptors [PDF]
A. Lisa SELBIE+3 more
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Evidence that neuronal G-protein-gated inwardly rectifying K+ channels are activated by Gβγ subunits and function as heteromultimers [PDF]
Guanine nucleotide-binding proteins (G proteins) activate K+ conductances in cardiac atrial cells to slow heart rate and in neurons to decrease excitability. cDNAs encoding three isoforms of a G-protein-coupled, inwardly rectifying K+ channel (GIRK) have
Davidson, Norman+2 more
core
Endothelial nitric oxide synthase interactions with G-protein-coupled receptors [PDF]
Mario B. Marrero+6 more
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Targeting of G Protein-coupled Receptors to the Basolateral Surface of Polarized Renal Epithelial Cells Involves Multiple, Non-contiguous Structural Signals [PDF]
Christine Saunders+3 more
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