Results 31 to 40 of about 18,235,278 (306)

Polymorphisms of the Serotonin Transporter Gene and G-Protein β3 Subunit Gene in Korean Children with Irritable Bowel Syndrome and Functional Dyspepsia

Gut and Liver, 2012
Background/AimsMany candidate gene studies have revealed that polymorphisms of the 5'-flanking controlled SERT gene linked polymorphic region (5HTT-LPR) gene and G-protein β3 C825T gene might be associated with functional dyspepsia (FD) and irritable ...
doaj   +1 more source

Mycobacterium tuberculosis CarD, an essential global transcriptional regulator forms amyloid-like fibrils

Scientific Reports, 2018
CarD is an essential global transcription regulator from Mycobacterium tuberculosis (Mtb) that binds RNA polymerase and activates transcription by stabilizing the transcription initiation complex.
Gundeep Kaur, Soni Kaundal, Srajan Kapoor, Jonathan M. Grimes, Juha T. Huiskonen, Krishan Gopal Thakur   +5 more
doaj   +1 more source

Expressed protein ligation for a large dimeric protein [PDF]

, 2011
Expressed protein ligation (EPL) is a protein engineering tool for post-translational ligation of protein or peptide fragments. This technique allows modification of specific parts of proteins, opening possibilities for incorporating probes for ...
NMR Spectroscopy, Karagöz, G.E., Sub Cellular Protein Chemistry, O. Hsieh, Sub NMR Spectroscopy, T. Sinnige, Rüdiger, S.G.D., Hsieh, O., Sinnige, T, G. E. Karagoz, S. G. D. Rudiger, Cellular Protein Chemistry   +11 more
core   +1 more source

Heterotrimeric G-Protein Signalers and RGSs in Aspergillus fumigatus

Pathogens, 2020
The heterotrimeric G-protein (G-protein) signaling pathway is one of the most important signaling pathways that transmit external signals into the inside of the cell, triggering appropriate biological responses. The external signals are sensed by various
Hee-Soo Park, Min-Ju Kim, Jae-Hyuk Yu, Kwang-Soo Shin   +3 more
doaj   +1 more source

Picky Hsp90-Every Game with Another Mate [PDF]

, 2017
In this issue of Molecular Cell, Sahasrabudhe et al. (2017) present a dramatically renovated functional cycle for the molecular chaperone Hsp90, which stimulates re-thinking of the mechanism of this vital protein folding ...
Sub Cellular Protein Chemistry, Rüdiger, Stefan G D, Radli, Martina, Cellular Protein Chemistry   +3 more
core   +2 more sources

The Disruption of a Gα Subunit Sheds New Light on the Pathogenicity of Stagonospora nodorum on Wheat

Molecular Plant-Microbe Interactions, 2004
Gna1, a gene encoding a Gα subunit, a key component of signal transduction pathways, has been cloned and characterized in the wheat pathogen Stagonospora nodorum.
Peter S. Solomon, Kar-Chun Tan, Pedro Sanchez, Richard M. Cooper, Richard P. Oliver   +4 more
doaj   +1 more source

DEER Analysis of GPCR Conformational Heterogeneity

Biomolecules, 2021
G protein-coupled receptors (GPCRs) represent a large class of transmembrane helical proteins which are involved in numerous physiological signaling pathways and therefore represent crucial pharmacological targets.
Matthias Elgeti, Wayne L. Hubbell
doaj   +1 more source

G-protein-linked fluctuating network of β₂AR.

, 2016
(A) Fluctuating atomsG-protein, which have a Pearson’s correlation coefficient of more than 0.6 between their ΔRMSF and G protein efficacy, are indicated by blue spheres.
Osamu Ichikawa (3169788), Kazuto Yamazaki (9494), Atsushi Yamada (282892), Kazushi Fujimoto (1730860), Susumu Okazaki (3169791)   +4 more
core   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Role of TAS2R38 polymorphism in respiratory diseases pathogenesis

Медицинская иммунология
More and more new data, concerning extraoral bitter taste receptors (TAS2R), appear now. Current data on polymorphisms, expression patterns and form of TAS2R subtype 38 (TAS2R38), its molecular variants that differ in the degrees of sensitivity to ...
M. A. Nyoma, R. G. Murkina, V. N. Mineev
doaj   +1 more source