Results 281 to 290 of about 12,561,590 (387)

Contribution of Gli1+ Adventitial Stem Cells to Smooth Muscle Cells in Atherosclerosis and Vascular Injury

Advanced Science, EarlyView.
Gli1+ adventitial stem cells (ASCs) have been thought to generate smooth muscle cells (SMCs) in atherosclerosis. Using a dual‐recombinase lineage tracing to exclude ectopic labeling, Wang et al. found that Gli1+ ASCs do not contribute to SMCs in atherosclerotic plaques.
Haixiao Wang, Xiuzhen Huang, Jialing Mou, Enci Wang, Yan Li, Wenjuan Pu, Yao Xie, Xiaoling Guo, Lixin Wang, Maoping Chu, Bin Zhou, Chao Niu   +11 more
wiley   +1 more source

RNA G-quadruplex (rG4) exacerbates cellular senescence by mediating ribosome pausing. [PDF]

Protein Cell
Zhou H, Wu S, Li B, Zhang R, Zou Y, Cao M, Xu A, Zheng K, Zhou Q, Wang J, Zheng J, Yang J, Ge Y, Lin Z, Ju Z.   +14 more
europepmc   +1 more source

Host‐Directed Antiviral Activity of SB2960 Through Selective Induction and Remodeling of Stress Granules

Advanced Science, EarlyView.
Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun, Sumin Son, JinAh Lee, Minha Lee, Meehyun Ko, Songrui Zhao, Ju Hee Kim, Kannan Vaithegi, Ji Hoon Kwon, Jung Ho Lee, Sangeun Jeon, Dawon Yi, Peng Zou, Seungtaek Kim, Seung Bum Park   +14 more
wiley   +1 more source

When the Position of Pendant Groups Makes the Difference in G-Quadruplex Behavior: The Case of Bis-Conjugated Thrombin-Binding Aptamers. [PDF]

J Chem Inf Model
Platella C, Battistini F, Riccardi C, Smietana M, Morvan F, Orozco M, Montesarchio D.   +6 more
europepmc   +1 more source

Supplementary Table S2 from G-Quadruplex Structures Are Key Modulators of Somatic Structural Variants in Cancers

Rongxin Zhang, Huiling Shu, Yuqi Wang, Tiantong Tao, Jing Tu, Cheng Wang, Jean‐Louis Mergny, Xiao Sun   +7 more
openalex   +1 more source

Folding pathways of hybrid-1 and hybrid-2 G-quadruplex structures [PDF]

, 2008
Tomoji Mashimo, Yasuo Sannohe, H. Yagi, H. Sugiyama   +3 more
openalex   +1 more source

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source

G-quadruplex structural motifs modulate protein-RNA interactions within the transcriptome. [PDF]

Genome Biol
Bhatt U, Evans CW, Cucchiarini A, Gros J, Iyer KS, Mergny JL, Smith NM.   +6 more
europepmc   +1 more source

Single‐Crystalline Borate Covalent Organic Frameworks for Solid‐State Lithium Metal Batteries

Advanced Science, EarlyView.
Advancing lithium metal batteries demands novel solid‐state electrolytes. Covalent organic frameworks (COFs) offer high ion conduction via porosity and functional groups. We synthesized single‐crystalline 3D borate COF with 8.1 mS cm−1 conductivity and 0.98 Li+ transference.
Ye Tian, Xiaolong Cheng, Lei Cheng, Yide Chang, Jixin Wu, Muhua Gu, Ki‐Taek Bang, Rui Wang, Ran Tao, Yufeng Wang, Soonyong So, Yanming Wang, Yoonseob Kim   +12 more
wiley   +1 more source

Deciphering the intermolecular interactions between G-quadruplex (G4)-forming sequences. [PDF]

Nucleic Acids Res
Xia J, Zhou J, Zhuang X, Ju H, Monchaud D, Chaires JB, Šponer J, Mergny JL, Zhou J.   +8 more
europepmc   +1 more source