Results 121 to 130 of about 9,085,971 (219)
In-line probing of RNA G-quadruplexes
, 2013 : Although the majority of the initial G-quadruplex studies were performed on DNA molecules, there currently exists a rapidly growing interest in the investigation of those formed in RNA molecules that possess high potential of acting as gene ...
Beaudoin, Jean-Denis +2 more
core +1 more source
Rôle des G-quadruplexes dans l'instabilité génomique chez Saccharomyces cerevisiae
, 2012 G-quadruplexes are topologically diverse four-stranded structures formed by certain G-rich nucleic acids in physiological conditions in vitro. During my thesis, I studied their in vivo formation, and the pathological consequences of their persistency ...
Piazza, Aurele
core +1 more source
Understanding the relationship between telomeres, telomerase, and DNA G-quadruplexes
, 2017 Cancer cells elongate their telomeres - G-rich repetitive sequences found at the end of linear chromosomes, allowing limitless replicative potential in these cells.
Moye, Aaron Lavel
core
A pyrene-based fast-responsive fluorescent probe for G-quadruplexes
, 2017 A novel pyrene-based fluorescent probe (3-methyl-2-(pyren-1-yl)benzo[d]thiazol-3-ium iodide) (PBT) was found to be a fast-responsive and highly selective towards G-quadruplexes.
Chuang Jiang, Xiao-Qi Yu, Ling-Ling Li
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Mechanical unfolding of individual bimolecular G-quadruplexes by AFM
, 2021 G‑quadruplexes (GQ) are non-canonical nucleic acids structures that form sequences rich in guanines, either in DNA or RNA. The prevalence of sequences able to form G-quadruplexes in crucial genomic sites suggests a significant role in important ...
Hubert, Sandrine
core
Telomeric G-quadruplexes are a substrate and site of localization for human telomerase
, 2016 It has been hypothesized that G-quadruplexes can sequester the 30 end of the telomere and prevent it from being extended by telomerase. Here we purify and characterize stable, conformationally homogenous human telomeric G-quadruplexes, and demonstrate ...
Karina C. Porter +8 more
core
Telomeric G-quadruplexes are a substrate and site of localization for human telomerase
, 2015 It has been hypothesized that G-quadruplexes can sequester the 3′ end of the telomere and prevent it from being extended by telomerase. Here we purify and characterize stable, conformationally homogenous human telomeric G-quadruplexes, and demonstrate ...
Tracy Bryan (20081034) +8 more
core
Bipyridine modified DNA G-quadruplexes
DNA G-quadruplexes are four-stranded secondary DNA structures formed through Hoogsten hydrogen bonds of four individual guanines, creating a G-tetrad whereby several of such tetrads can stack on top of each other to create the final construct.
Durmisevic, Armin
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Visualizing cellular G-quadruplexes with a bioinspired chemiluminescent probe. [PDF]
Nucleic Acids ResWang P +6 more
europepmc +1 more source
Computational and Experimental Characterization of rDNA and rRNA G‑Quadruplexes
DNA G-quadruplexes in human telomeres and gene promoters are being extensively studied for their role in controlling the growth of cancer cells. G-quadruplexes have been unambiguously shown to exist both in vitro and in vivo, including in the guanine (G)-
Samuel S. Cho (1894093) +5 more
core +1 more source