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2019
The expression of Mgmt gene was investigated by Western blot analysis in the spontaneously immortalized mouse cell line G1 and in its sublines G1-OA and G1-T at different passages of in vitro cultivation. The highest level of Mgmt expression has been revealed in G1-T subline cells and the lowest ??? in G1-OA subline cells.
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The expression of Mgmt gene was investigated by Western blot analysis in the spontaneously immortalized mouse cell line G1 and in its sublines G1-OA and G1-T at different passages of in vitro cultivation. The highest level of Mgmt expression has been revealed in G1-T subline cells and the lowest ??? in G1-OA subline cells.
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2019
Cytogenetic analysis of the spontaneously immortalized mouse cell line G1 has been carried out on passages 15, 24, 53, 68, 104 and 140 of in vitro cultivation. G1 cells were revealed to have quantitative chromosome changes, different chromosomal aberrations, and a particularly high percentage of Robertsonian translocations.
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Cytogenetic analysis of the spontaneously immortalized mouse cell line G1 has been carried out on passages 15, 24, 53, 68, 104 and 140 of in vitro cultivation. G1 cells were revealed to have quantitative chromosome changes, different chromosomal aberrations, and a particularly high percentage of Robertsonian translocations.
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2015
Growth and morphological properties of a novel mouse cell line G1 have been investigated. It has been shown that cells of this cell line possess the ability of spontaneous transformation in vitro: the cells have unlimited growth in culture, grow in medium with a low serum content and form multilayer colonies on a cell monolayer and cell colonies inside
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Growth and morphological properties of a novel mouse cell line G1 have been investigated. It has been shown that cells of this cell line possess the ability of spontaneous transformation in vitro: the cells have unlimited growth in culture, grow in medium with a low serum content and form multilayer colonies on a cell monolayer and cell colonies inside
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2019
?????????????? ???????????????????????? ?????????????? ???????????? ?????????? G1 ?????? ?????????????????? ???????????????????? ?? ???????????? ??????????????????????????. ?????????????????????? ?????????????? ???????????????????????????????? ?? ???????????????? ?????????????????? ???????????? ?????????? G1 ???? 26-?? ?? 114-?? ???????????????? ???? ??
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?????????????? ???????????????????????? ?????????????? ???????????? ?????????? G1 ?????? ?????????????????? ???????????????????? ?? ???????????? ??????????????????????????. ?????????????????????? ?????????????? ???????????????????????????????? ?? ???????????????? ?????????????????? ???????????? ?????????? G1 ???? 26-?? ?? 114-?? ???????????????? ???? ??
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2008
The effect of antitumor drug, taxol, on the activity of cell cycle regulatory factors in two cell lines of anaplastic thyroid cancer ARO and KTC-2 is studied. It is shown that taxol enhances the phosphorylation of retinoblastoma protein, pRB, in both cell lines.
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The effect of antitumor drug, taxol, on the activity of cell cycle regulatory factors in two cell lines of anaplastic thyroid cancer ARO and KTC-2 is studied. It is shown that taxol enhances the phosphorylation of retinoblastoma protein, pRB, in both cell lines.
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