Results 41 to 50 of about 1,376,328 (285)

Coherence properties of the microcavity polariton condensate [PDF]

, 2008
A theoretical model is presented which explains the dominant decoherence process in a microcavity polariton condensate. The mechanism which is invoked is the effect of self-phase modulation, whereby interactions transform polariton number fluctuations ...
Callen H. B., D. M. Whittaker, P. R. Eastham, Scully M. O.   +3 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

The Impact of Inflation on Financial Sector Performance: Evidence from OECD Countries

ECONOMICS
This research article investigates the relationship between inflation and the performance of the financial sector within OECD countries, a group critical to global economic stability.
Bilalli Argjira, Sadiku Murat, Sadiku Luljeta   +2 more
doaj   +1 more source

Addressing Frequency Control Challenges in Future Low-Inertia Power Systems: A Great Britain Perspective

Engineering, 2021
The ambitious global targets on decarbonization present the need for massive integration of renewable generation in power systems, resulting in a significant decrease in the system inertia. In addition to the reduction in system inertia, the transmission
Qiteng Hong, Md Asif Uddin Khan, Callum Henderson, Agustí Egea-Àlvarez, Dimitrios Tzelepis, Campbell Booth   +5 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

The Limitations of the G1-S Checkpoint [PDF]

Cancer Research, 2010
Abstract It has been proposed that the G1-S checkpoint is the critical regulator of genomic stability, preventing the cell cycle progression of cells with a single DNA double-strand break. Using fluorescence-activated cell sorting analysis of asynchronous cells and microscopic analysis of asynchronous and synchronized cells, we show ...
Dorothee, Deckbar, Thomas, Stiff, Barbara, Koch, Caroline, Reis, Markus, Löbrich, Penny A, Jeggo   +5 more
openaire   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The Relationship Between Interest Rates, Financial Ratios, and Bond Ratings with Profitability as a Mediating Variables in Non-Financial Sector Companies in Indonesia

ECONOMICS
During the latest decades, regional creativity has often been considThis study seeks to investigate the relationship between interest rates, liquidity, and leverage to non-financial companies in Indonesia who have issued bond securities between 2018 and ...
Marjohan Masno, Sampurnaningsih Sri Retnaning   +1 more
doaj   +1 more source

Outlier identification in radiation therapy knowledge-based planning: A study of pelvic cases. [PDF]

, 2017
PURPOSE: The purpose of this study was to apply statistical metrics to identify outliers and to investigate the impact of outliers on knowledge-based planning in radiation therapy of pelvic cases.
Aggarwal, Appenzoller, Barnett, Boutilier, Chanyavanich, Delaney, Fogliata, Hawkins, Hodge, Lian, Motulsky, Osborne, Pardoe, Sheng, Sheng, Tol, Wang, Whittingham, Wu, Yang, Youden, Yuan, Yuan, Zhu   +23 more
core   +2 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source