Results 51 to 60 of about 1,376,328 (285)

A Stochastic Method for Optimizing Portfolios Using a Combined Monte Carlo and Markowitz Model: Approach on Python

ECONOMICS
The main of the study is to comprehend how the mean variance efficient frontier method may be used in conjunction with Markowitz portfolio theory to produce an optimal portfolio.
Mallieswari R., Palanisamy Varadharajan, Senthilnathan Arthi Thangavelu, Gurumurthy Suganya, Joshua Selvakumar J., Pachiyappan Sathish   +5 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

G1 Cosmologies with Gravitational and Scalar Waves

, 1998
I present here a new algorithm to generate families of inhomogeneous massless scalar field cosmologies. New spacetimes, having a single isometry, are generated by breaking the homogeneity of massless scalar field $G_2$ models along one direction.
A. Albrecht, A. D. Linde, A. D. Linde, A. Feinstein, A. Feinstein, A. G. Doroshkevich, A. H. Guth, A. Krasinski, B. K. Berger, B. K. Berger, B. K. Berger, B. K. Berger, B. K. Berger, B. K. Berger, B. K. Berger, C. W. Misner, C. W. Misner, C. W. Misner, Ch. Charach, Ch. Charach, Ch. Charach, D. Clancy, D. Kramer, E. P. Liang, E. Verdaguer, G. A. Alekseev, J. B. Griffiths, J. B. Griffiths, J. Bičák, J. Bičák, J. Centrella, J. Centrella, J. Centrella, J. D. Barrow, J. M. Bardeen, J. M. Stewart, J. Wainwright, M. Carmeli, M. Carmeli, M. Carmeli, M. Gasperini, M. Weaver, P. S. Letelier, R. Gowdy, R. Gowdy, R. Gregory, R. Tabenski, Ruth Lazkoz, S. D. Hern, V. A. Belinskii, V. A. Belinskii, V. A. Belinskii, V. A. Belinskii, V. A. Belinskii, V. A. Belinskii, V. A. Belinskii, V. F. Muknanov, W. B. Bonnor, Wu Zhong Chao   +58 more
core   +1 more source

First Lattice QCD Study of the Sigma -> n Axial and Vector Form Factors with SU(3) Breaking Corrections [PDF]

, 2006
We present the first quenched lattice QCD study of the form factors relevant for the hyperon semileptonic decay Sigma -> n l nu. The momentum dependence of both axial and vector form factors is investigated and the values of all the form factors at zero ...
Guadagnoli, D., Lubicz, V., Papinutto, M., Simula, S.   +3 more
core   +4 more sources

G1 cyclins protect pluripotency [PDF]

Nature Cell Biology, 2017
G1 cyclins are considered essential for DNA replication and cell division. A recent report now shows that some cells can cycle in the absence of G1 cyclins. In embryonic stem cells and cancer cells, G1 cyclins are required to activate cyclin-dependent kinases to phosphorylate core pluripotency factors and maintain pluripotency.
Julia, Arand, Julien, Sage
openaire   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Google Search intensity and stock returns in frontier markets: Evidence from the Vietnamese market1

Economics and Business Review
The study investigates the impact of investor attention on stock trading by modeling the relationship between Google Search intensity and stock return with stocks listed in frontier markets in Vietnam from October 2016 to October 2021.
Duc Dang Thi Viet, Hoai Nguyen Thu, Nguyen Van Phuoc, Nguyen Dang Phong, Anh Nguyen Huong, Hai Ho Hong   +5 more
doaj   +1 more source

Effect of S-triazine Ring Substitution on the Synthesis of Organic Resorcinol-Formaldehyde Xerogels

Gels, 2020
Resorcinol (R) and formaldehyde (F) gel synthesis has been well-studied along with alternative reagents. We present the synthesis of formaldehyde-based xerogels using chemically similar s-triazine precursors, with comparison to traditional analogues. The
Martin Prostredný, Caio Ledingham, Ivan A. Principe, Abdelkarim S. M. Altoumi, Ashleigh J. Fletcher   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Crack Monitoring of Operational Wind Turbine Foundations

Sensors, 2017
The degradation of onshore, reinforced-concrete wind turbine foundations is usually assessed via above-ground inspections, or through lengthy excavation campaigns that suspend wind power generation.
Marcus Perry, Jack McAlorum, Grzegorz Fusiek, Pawel Niewczas, Iain McKeeman, Tim Rubert   +5 more
doaj   +1 more source