Results 91 to 100 of about 7,531,916 (333)

Initial characterization of gap phase introduction in every cell cycle of C. elegans embryogenesis

Frontiers in Cell and Developmental Biology, 2022
Early embryonic cell cycles usually alternate between S and M phases without any gap phase. When the gap phases are developmentally introduced in various cell types remains poorly defined especially during embryogenesis.
Ming-Kin Wong, Vincy Wing Sze Ho, Xiaotai Huang, Xiaotai Huang, Lu-Yan Chan, Dongying Xie, Runsheng Li, Xiaoliang Ren, Guoye Guan, Yiming Ma, Boyi Hu, Boyi Hu, Hong Yan, Zhongying Zhao, Zhongying Zhao   +14 more
doaj   +1 more source

The epigenetic control of E-box and Myc-dependent chromatin modifications regulate the licensing of lamin B2 origin during cell cycle [PDF]

, 2012
Recent genome-wide mapping of the mammalian replication origins has suggested the role of transcriptional regulatory elements in origin activation. However, the nature of chromatin modifications associated with such trans-factors or epigenetic marks ...
Kumar, V, Singh, AK, Swarnalatha, M
core   +1 more source

Magnetic Shielding Accelerates the Proliferation of Human Neuroblastoma Cell by Promoting G1-Phase Progression

PLoS ONE, 2013
Organisms have been exposed to the geomagnetic field (GMF) throughout evolutionary history. Exposure to the hypomagnetic field (HMF) by deep magnetic shielding has recently been suggested to have a negative effect on the structure and function of the ...
Wei-chuan Mo, Zi-jian Zhang, Y. Liu, P. Bartlett, R. He   +4 more
semanticscholar   +1 more source

The Temporal Regulation of S Phase Proteins During G1 [PDF]

, 2017
Successful DNA replication requires intimate coordination with cell-cycle progression. Prior to DNA replication initiation in S phase, a series of essential preparatory events in G1 phase ensures timely, complete, and precise genome duplication. Among the essential molecular processes are regulated transcriptional upregulation of genes that encode ...
Gavin D, Grant, Jeanette G, Cook
openaire   +2 more sources

S-phase function of Drosophila cyclin A and its downregulation in G1 phase [PDF]

Current Biology, 1997
Cyclin E is the normal inducer of S phase in G1 cells of Drosophila embryos. Stable G1 quiescence requires the downregulation both of cyclin E and of other factors that can bypass the normal regulation of cell cycle progression.High-level expression of cyclin A triggered the G1/S transition in wild-type embryos and in mutant embryos lacking cyclin E ...
Sprenger, Frank, Yakubovich, Nikita, O’Farrell, Patrick H.   +2 more
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

BRCA1-Ku80 Protein Interaction Enhances End-joining Fidelity of Chromosomal Double-strand Breaks in the G1 Phase of the Cell Cycle*

Journal of Biological Chemistry, 2013
Background: Quality control of DNA double-strand break repair is poorly understood. Results: BRCA1 enhances the fidelity of NHEJ repair and prevents mutagenic deletional end-joining through interaction with canonical NHEJ machinery during G1. Conclusion:
G. Jiang, I. Plo, Tong Wang, M. Rahman, J. Cho, E. Yang, B. Lopez, F. Xia   +7 more
semanticscholar   +1 more source

REAPPRAISAL OF G1‐PHASE ARREST AND SYNCHRONIZATION BY LOVASTATIN [PDF]

Cell Biology International, 2002
AbstractIt has been proposed that lovastatin arrests cells in the G1‐phase of the division cycle, and that release from lovastatin inhibition produces a synchronized culture. A new method of methocel time‐lapse‐videography has been used to analyse cell division patterns following lovastatin treatment.
openaire   +3 more sources

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Study of Ultraviolet-Induces Chromatid and Chromosome Aberrations as a Function of Dose in G1 Phase Vertebrate Tissue Cultures [PDF]

, 1976
G1 phase A8 Xenopus laevis (toad) and V79B Cricetulus griseus (hamster) tissue cultures were used to observe the frequency of ultraviolet-induced chromosomal aberrations as a function of dose.
Griggs, H. Gaston, Orr, Troy V.
core   +2 more sources